Nomenclature of blood monocytes
Human . | Mouse* . |
---|---|
Classical CD14++CD16− monocytes | Classical Ly6C++ CD43+ monocytes |
Intermediate CD14++CD16+ monocytes | Intermediate Ly6C++ CD43++ monocytes |
Nonclassical CD14+CD16++ monocytes | Nonclassical Ly6C+ CD43++ monocytes |
Human . | Mouse* . |
---|---|
Classical CD14++CD16− monocytes | Classical Ly6C++ CD43+ monocytes |
Intermediate CD14++CD16+ monocytes | Intermediate Ly6C++ CD43++ monocytes |
Nonclassical CD14+CD16++ monocytes | Nonclassical Ly6C+ CD43++ monocytes |
The CD markers given are considered most appropriate at this time. They may be superseded by superior reagents in the future. The + denotes an expression level that is ∼ 10-fold above the isotype control and ++ is ∼ 100-fold above the isotype control.
Additional markers have to be used to define the cells under study as monocytes (see text).