Table 1

Clinical characteristics of 53 patients with classical Hodgkin lymphoma analyzed by the use of array comparative genomic hybridization

All patientsTreatment successTreatment failureP
n (%) 53 30 (57) 23 (43)  
Median age, y (range) 36 36 (15-74) 29 (12-71) .559 
Male sex, % 66 56 78 .100 
Histology, %    .831 
    Nodular sclerosis 82 87 78  
    Mixed cellularity  
    Lymphocyte rich  
    Lymphocyte depleted  
    NOS  
Advanced stage, % 62 40 91 < .001* 
B symptoms, % 30 20 43 .065 
IPS 4 or more, high-risk 17 13 22 .419 
Mass size, median (range) in cm .210 
    10 or more cm, % 25 23 26 1.000 
Treatment    .249 
    ABVD type ± radiation, % 94 90 100  
    Extended-field radiation alone, % 10  
All patientsTreatment successTreatment failureP
n (%) 53 30 (57) 23 (43)  
Median age, y (range) 36 36 (15-74) 29 (12-71) .559 
Male sex, % 66 56 78 .100 
Histology, %    .831 
    Nodular sclerosis 82 87 78  
    Mixed cellularity  
    Lymphocyte rich  
    Lymphocyte depleted  
    NOS  
Advanced stage, % 62 40 91 < .001* 
B symptoms, % 30 20 43 .065 
IPS 4 or more, high-risk 17 13 22 .419 
Mass size, median (range) in cm .210 
    10 or more cm, % 25 23 26 1.000 
Treatment    .249 
    ABVD type ± radiation, % 94 90 100  
    Extended-field radiation alone, % 10  

ABVD indicates doxorubicin, bleomycin, vinblastine, and dacarbazine; IPS, International Prognostic Scoring; and NOS, not otherwise specified.

*

Statistically significant.

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