Cardiovascular risk factors among 635 control subjects and the association with α2-antiplasmin and plasminogen levels
Characteristic . | n . | α2-Antiplasmin level . | Plasminogen level . | ||
---|---|---|---|---|---|
Mean . | 5th-95th percentile . | Mean . | 5th-95th percentile . | ||
Age, y | |||||
27-39 | 54 | 104 | 84-122 | 93 | 74-107 |
40-49 | 103 | 98 | 80-121 | 94 | 77-113 |
50-59 | 178* | 97 | 77-115 | 97 | 78-114 |
60-69 | 243 | 93 | 74-114 | 94 | 77-114 |
70-75 | 57 | 90 | 78-108 | 91 | 72-115 |
BMI, kg/m2† | |||||
Less than 20 | 10 | 97 | 74-115 | 99 | 79-115 |
20-24 | 182 | 94 | 74-112 | 92 | 72-112 |
25-29 | 341 | 96 | 78-116 | 94 | 78-112 |
At least 30 | 101* | 98 | 78-123 | 98 | 80-116 |
Diabetes | |||||
No | 614* | 96 | 77-116 | 94 | 77-113 |
Yes | 21 | 95 | 78-123 | 92 | 70-113 |
Diastolic blood pressure, mm Hg‡ | |||||
Less than 80 | 199 | 96 | 76-119 | 93 | 77-115 |
85 | 90* | 96 | 81-116 | 96 | 76-114 |
90 | 167 | 94 | 74-114 | 93 | 74-114 |
At least 95 | 174 | 97 | 78-116 | 96 | 78-112 |
Systolic blood pressuremm Hg‡ | |||||
Less than 125 | 157 | 98 | 75-121 | 94 | 76-113 |
130-135 | 114 | 95 | 77-116 | 94 | 80-109 |
140-150 | 200* | 96 | 78-115 | 94 | 75-115 |
At least 155 | 159 | 93 | 78-112 | 95 | 76-115 |
Triglycerides, mmol/L† | |||||
Less than 0.90 | 157 | 94 | 74-115 | 90 | 72-109 |
0.90-1.24 | 159 | 95 | 76-113 | 94 | 76-111 |
1.25-1.82 | 161 | 96 | 78-117 | 96 | 80-115 |
At least 1.83 | 157 | 98 | 81-118 | 98 | 81-116 |
Total cholesterol, mmol/L† | |||||
Less than 5.17 | 161 | 94 | 75-113 | 91 | 72-111 |
5.17-5.81 | 156 | 95 | 76-117 | 93 | 76-111 |
5.82-6.59 | 157 | 97 | 80-119 | 94 | 79-110 |
At least 6.60 | 160 | 98 | 80-118 | 99 | 84-116 |
HDL cholesterol, mmol/L§ | |||||
Less than 1.1 | 159 | 98 | 78-116 | 95 | 76-116 |
1.1-1.28 | 156 | 97 | 80-119 | 94 | 76-113 |
1.29-1.53 | 162 | 94 | 73-114 | 94 | 76-112 |
At least 1.54 | 155 | 95 | 78-117 | 94 | 78-115 |
C-reactive protein, mg/L | |||||
Less than 0.78 | 159 | 95 | 74-113 | 89 | 74-108 |
0.78-1.55 | 161 | 96 | 78-116 | 93 | 78-107 |
1.56-3.42 | 159* | 96 | 78-119 | 95 | 76-119 |
At least 3.43 | 156 | 96 | 78-116 | 101 | 85-118 |
Smoking | |||||
No | 426* | 96 | 78-117 | 93 | 76-112 |
Yes | 209 | 95 | 75-115 | 98 | 80-116 |
Alcohol use | |||||
No | 64 | 96 | 79-117 | 92 | 74-111 |
Occasionally | 20 | 95 | 55-123 | 89 | 70-106 |
Yes | 551* | 96 | 77-116 | 95 | 77-114 |
VWF‖ | |||||
Less than 97% | 159 | 97 | 77-117 | 92 | 74-108 |
98%-124% | 151 | 97 | 81-118 | 94 | 78-114 |
125%-158% | 145 | 96 | 74-114 | 96 | 77-115 |
At least 159% | 152 | 93 | 75-114 | 96 | 77-117 |
Plasminogen* | |||||
Less than 87% | 171 | 91 | 74-109 | ||
87%-93% | 152 | 95 | 76-114 | ||
94%-100% | 155 | 97 | 81-116 | ||
At least 101% | 156 | 100 | 81-120 | ||
α2-antiplasmin | |||||
Less than 87% | 163 | 91 | 72-109 | ||
87%-94% | 163 | 93 | 76-112 | ||
95%-104% | 153 | 95 | 76-113 | ||
At least 105% | 155 | 99 | 84v116 |
Characteristic . | n . | α2-Antiplasmin level . | Plasminogen level . | ||
---|---|---|---|---|---|
Mean . | 5th-95th percentile . | Mean . | 5th-95th percentile . | ||
Age, y | |||||
27-39 | 54 | 104 | 84-122 | 93 | 74-107 |
40-49 | 103 | 98 | 80-121 | 94 | 77-113 |
50-59 | 178* | 97 | 77-115 | 97 | 78-114 |
60-69 | 243 | 93 | 74-114 | 94 | 77-114 |
70-75 | 57 | 90 | 78-108 | 91 | 72-115 |
BMI, kg/m2† | |||||
Less than 20 | 10 | 97 | 74-115 | 99 | 79-115 |
20-24 | 182 | 94 | 74-112 | 92 | 72-112 |
25-29 | 341 | 96 | 78-116 | 94 | 78-112 |
At least 30 | 101* | 98 | 78-123 | 98 | 80-116 |
Diabetes | |||||
No | 614* | 96 | 77-116 | 94 | 77-113 |
Yes | 21 | 95 | 78-123 | 92 | 70-113 |
Diastolic blood pressure, mm Hg‡ | |||||
Less than 80 | 199 | 96 | 76-119 | 93 | 77-115 |
85 | 90* | 96 | 81-116 | 96 | 76-114 |
90 | 167 | 94 | 74-114 | 93 | 74-114 |
At least 95 | 174 | 97 | 78-116 | 96 | 78-112 |
Systolic blood pressuremm Hg‡ | |||||
Less than 125 | 157 | 98 | 75-121 | 94 | 76-113 |
130-135 | 114 | 95 | 77-116 | 94 | 80-109 |
140-150 | 200* | 96 | 78-115 | 94 | 75-115 |
At least 155 | 159 | 93 | 78-112 | 95 | 76-115 |
Triglycerides, mmol/L† | |||||
Less than 0.90 | 157 | 94 | 74-115 | 90 | 72-109 |
0.90-1.24 | 159 | 95 | 76-113 | 94 | 76-111 |
1.25-1.82 | 161 | 96 | 78-117 | 96 | 80-115 |
At least 1.83 | 157 | 98 | 81-118 | 98 | 81-116 |
Total cholesterol, mmol/L† | |||||
Less than 5.17 | 161 | 94 | 75-113 | 91 | 72-111 |
5.17-5.81 | 156 | 95 | 76-117 | 93 | 76-111 |
5.82-6.59 | 157 | 97 | 80-119 | 94 | 79-110 |
At least 6.60 | 160 | 98 | 80-118 | 99 | 84-116 |
HDL cholesterol, mmol/L§ | |||||
Less than 1.1 | 159 | 98 | 78-116 | 95 | 76-116 |
1.1-1.28 | 156 | 97 | 80-119 | 94 | 76-113 |
1.29-1.53 | 162 | 94 | 73-114 | 94 | 76-112 |
At least 1.54 | 155 | 95 | 78-117 | 94 | 78-115 |
C-reactive protein, mg/L | |||||
Less than 0.78 | 159 | 95 | 74-113 | 89 | 74-108 |
0.78-1.55 | 161 | 96 | 78-116 | 93 | 78-107 |
1.56-3.42 | 159* | 96 | 78-119 | 95 | 76-119 |
At least 3.43 | 156 | 96 | 78-116 | 101 | 85-118 |
Smoking | |||||
No | 426* | 96 | 78-117 | 93 | 76-112 |
Yes | 209 | 95 | 75-115 | 98 | 80-116 |
Alcohol use | |||||
No | 64 | 96 | 79-117 | 92 | 74-111 |
Occasionally | 20 | 95 | 55-123 | 89 | 70-106 |
Yes | 551* | 96 | 77-116 | 95 | 77-114 |
VWF‖ | |||||
Less than 97% | 159 | 97 | 77-117 | 92 | 74-108 |
98%-124% | 151 | 97 | 81-118 | 94 | 78-114 |
125%-158% | 145 | 96 | 74-114 | 96 | 77-115 |
At least 159% | 152 | 93 | 75-114 | 96 | 77-117 |
Plasminogen* | |||||
Less than 87% | 171 | 91 | 74-109 | ||
87%-93% | 152 | 95 | 76-114 | ||
94%-100% | 155 | 97 | 81-116 | ||
At least 101% | 156 | 100 | 81-120 | ||
α2-antiplasmin | |||||
Less than 87% | 163 | 91 | 72-109 | ||
87%-94% | 163 | 93 | 76-112 | ||
95%-104% | 153 | 95 | 76-113 | ||
At least 105% | 155 | 99 | 84v116 |
BMI indicates body mass index; HDL, high-density lipoprotein; and VWF, von Willebrand factor.
Plasminogen levels were missing for 1 control subject.
BMI was missing for 1 control subject.
Systolic and diastolic blood pressures were missing for 5 control subjects.
HDL cholesterol was missing for 3 control subjects.
VWF was missing for 28 control subjects.