Risk of myocardial infarction with increasing quartiles of PAI-1
| . | Q1 . | Q2 . | Q3 . | Q4 . |
|---|---|---|---|---|
| Cutoff, ng/mL | 32.9 | 54.9 | 99.0 | |
| No. of patients | 118 | 109 | 121 | 202 |
| No. of control subjects | 158 | 159 | 159 | 158 |
| Model 1: age, OR (95% CI) | 1 | 0.9 (0.7-1.3) | 1.0 (0.7-1.4) | 1.7 (1.2-2.3) |
| Model 2: model 1 + HDL and total cholesterol, triglycerides, BMI, and diabetes, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.6) |
| Model 3: model 2 + CRP, VWF, systolic and diastolic blood pressures, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.7) |
| Model 4: model 3 + t-PA, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.7) |
| . | Q1 . | Q2 . | Q3 . | Q4 . |
|---|---|---|---|---|
| Cutoff, ng/mL | 32.9 | 54.9 | 99.0 | |
| No. of patients | 118 | 109 | 121 | 202 |
| No. of control subjects | 158 | 159 | 159 | 158 |
| Model 1: age, OR (95% CI) | 1 | 0.9 (0.7-1.3) | 1.0 (0.7-1.4) | 1.7 (1.2-2.3) |
| Model 2: model 1 + HDL and total cholesterol, triglycerides, BMI, and diabetes, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.6) |
| Model 3: model 2 + CRP, VWF, systolic and diastolic blood pressures, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.7) |
| Model 4: model 3 + t-PA, OR (95% CI) | 1 | 0.8 (0.6-1.2) | 0.8 (0.6-1.2) | 1.1 (0.8-1.7) |
PAI-1 levels were missing for 1 control subject and 5 patients.
PAI-1 indicates plasminogen activator inhibitor 1; Q, quartile, HDL, high-density lipoprotein; BMI, body mass index; CRP, C-reactive protein; VWF, von Willebrand factor; and t-PA, tissue plasminogen activator.