χ2 comparisons of individual IGHV genes between four different populations of B cells†
| IGHV names . | T versus N . | T versus S . | T versus M . | N versus S . | N versus M . | S versus M . |
|---|---|---|---|---|---|---|
| IGHV1-18 | ** | *** | * | *** | *** | |
| IGHV1-2 | ** | *** | ** | *** | *** | |
| IGHV1-24 | * | |||||
| IGHV1-3 | * | *** | *** | |||
| IGHV1-46 | *** | *** | * | *** | ||
| IGHV1-58 | * | * | ** | |||
| IGHV1-69 | * | ** | *** | *** | *** | |
| IGHV1-8 | * | ** | * | |||
| IGHV2-26 | ||||||
| IGHV2-5 | * | *** | *** | |||
| IGHV2-70 | * | |||||
| IGHV3-11 | * | ** | * | |||
| IGHV3-13 | *** | * | * | * | ||
| IGHV3-15 | * | |||||
| IGHV3-20 | * | |||||
| IGHV3-21 | ||||||
| IGHV3-23 | * | *** | *** | *** | ||
| IGHV3-30 | * | ** | ||||
| IGHV3-30-3 | ** | *** | ** | |||
| IGHV3-33 | *** | *** | *** | *** | ||
| IGHV3-43 | * | |||||
| IGHV3-48 | * | ** | *** | |||
| IGHV3-49 | * | ** | ||||
| IGHV3-53 | ||||||
| IGHV3-64 | ||||||
| IGHV3-66 | ** | *** | *** | |||
| IGHV3-7 | * | * | *** | |||
| IGHV3-71 | ||||||
| IGHV3-72 | * | |||||
| IGHV3-73 | ||||||
| IGHV3-74 | * | *** | ** | |||
| IGHV3-9 | ** | |||||
| IGHV3-h | ||||||
| IGHV4-28 | ||||||
| IGHV4-30-2 | * | * | * | |||
| IGHV4-30-4 | ** | *** | ** | |||
| IGHV4-31 | ** | *** | ** | |||
| IGHV4-34 | ** | * | ||||
| IGHV4-39 | ||||||
| IGHV4-4 | ||||||
| IGHV4-55 | ||||||
| IGHV4-59 | ||||||
| IGHV4-61 | * | * | ||||
| IGHV4-b | * | * | ||||
| IGHV5-51 | * | |||||
| IGHV5-a | ** | * | ||||
| IGHV6-1 | * | * | ||||
| IGHV7-4-1 | * | * |
| IGHV names . | T versus N . | T versus S . | T versus M . | N versus S . | N versus M . | S versus M . |
|---|---|---|---|---|---|---|
| IGHV1-18 | ** | *** | * | *** | *** | |
| IGHV1-2 | ** | *** | ** | *** | *** | |
| IGHV1-24 | * | |||||
| IGHV1-3 | * | *** | *** | |||
| IGHV1-46 | *** | *** | * | *** | ||
| IGHV1-58 | * | * | ** | |||
| IGHV1-69 | * | ** | *** | *** | *** | |
| IGHV1-8 | * | ** | * | |||
| IGHV2-26 | ||||||
| IGHV2-5 | * | *** | *** | |||
| IGHV2-70 | * | |||||
| IGHV3-11 | * | ** | * | |||
| IGHV3-13 | *** | * | * | * | ||
| IGHV3-15 | * | |||||
| IGHV3-20 | * | |||||
| IGHV3-21 | ||||||
| IGHV3-23 | * | *** | *** | *** | ||
| IGHV3-30 | * | ** | ||||
| IGHV3-30-3 | ** | *** | ** | |||
| IGHV3-33 | *** | *** | *** | *** | ||
| IGHV3-43 | * | |||||
| IGHV3-48 | * | ** | *** | |||
| IGHV3-49 | * | ** | ||||
| IGHV3-53 | ||||||
| IGHV3-64 | ||||||
| IGHV3-66 | ** | *** | *** | |||
| IGHV3-7 | * | * | *** | |||
| IGHV3-71 | ||||||
| IGHV3-72 | * | |||||
| IGHV3-73 | ||||||
| IGHV3-74 | * | *** | ** | |||
| IGHV3-9 | ** | |||||
| IGHV3-h | ||||||
| IGHV4-28 | ||||||
| IGHV4-30-2 | * | * | * | |||
| IGHV4-30-4 | ** | *** | ** | |||
| IGHV4-31 | ** | *** | ** | |||
| IGHV4-34 | ** | * | ||||
| IGHV4-39 | ||||||
| IGHV4-4 | ||||||
| IGHV4-55 | ||||||
| IGHV4-59 | ||||||
| IGHV4-61 | * | * | ||||
| IGHV4-b | * | * | ||||
| IGHV5-51 | * | |||||
| IGHV5-a | ** | * | ||||
| IGHV6-1 | * | * | ||||
| IGHV7-4-1 | * | * |
Transitional (T, n = 433), naive (N, n = 662), switched memory (S, n = 1293) and IgM memory (M, n = 1209) populations were compared with each other.
P < .05; **P < .005; ***P < .0005. Note that if Bonferroni correction is applied the comparisons marked * are no longer considered to be significant. Some of these P values are the result of a trend in the 3 separate donors that individually did not reach significance. Those that are bold indicate that the P values of more than 1 of the donors reached significance individually (supplemental Table 3).