Table 1

Clinical characteristics at HU start

CharacteristicValue
Patients, N 416 
Sex, male/female, n (%) 154/262 (37/63) 
Median age, y (range) 66 (18-95) 
    Less than 40 24 (6) 
    40-60 119 (28) 
    More than 60 273 (66) 
JAK2 V617F/JAK2* wt, n (%) 231/148 (61/39) 
Patients with thrombosis, n (%) 161 (39) 
    AMI 32 (20) 
    Stroke/TIA 77 (48) 
    PAT 16 (10) 
    VTE 36 (22) 
Median time from diagnosis to HU start, mo (range) 4.9 (0-255) 
    Less than 1 y, n (%) 258 (62) 
    1-5 y, n (%) 108 (26) 
    More than 5 y, n (%) 50 (12) 
Patients on aspirin, n (%) 324 (78) 
CharacteristicValue
Patients, N 416 
Sex, male/female, n (%) 154/262 (37/63) 
Median age, y (range) 66 (18-95) 
    Less than 40 24 (6) 
    40-60 119 (28) 
    More than 60 273 (66) 
JAK2 V617F/JAK2* wt, n (%) 231/148 (61/39) 
Patients with thrombosis, n (%) 161 (39) 
    AMI 32 (20) 
    Stroke/TIA 77 (48) 
    PAT 16 (10) 
    VTE 36 (22) 
Median time from diagnosis to HU start, mo (range) 4.9 (0-255) 
    Less than 1 y, n (%) 258 (62) 
    1-5 y, n (%) 108 (26) 
    More than 5 y, n (%) 50 (12) 
Patients on aspirin, n (%) 324 (78) 

AMI indicates acute myocardial infarction; TIA, cerebral transient ischemic attack; PAT, peripheral arterial thrombosis; and VTE, venous thromboembolism.

*

Percentages calculated on 379 JAK2 V617F evaluated patients.

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