Table 3 Cases who developed ATL from... | American Society of Hematology

Table 3

Cases who developed ATL from HTLV-I carrier status

Case no.	Demographic characteristics						Baseline clinical and biologic values					ATL development
Case no.	Sex	Age, y	Place of birth	First opportunity for HTLV-1 testing	Family history of HTLV-1–related disease	Comorbidity at enrollment	HTLV-1 VL, copies/100 PBMCs	sIL-2R, U/mL	Abnormal lymphocytes, percentage	LDH, IU/L	WBC, ×10³/mm³	Clinical type	Duration from enrollment, mo
Progression to aggressive type of ATL
1	M	79.9	Southern	ATL family	ATL	None	5.47	479	2	157	4200	Acute	7.4
2	F	70.3	Southern	ATL family	ATL	None	4.73	904	0	365	9130	Acute	38.6
3	M	71.9	Southern	Other disease	None	Skin disease	4.17	1450	0	351	5140	Lymph	4.6
4	F	75.8	Southern	Unknown	Unknown	None	10.52	2080	3	308	3600	Lymph	30.6
Progression to indolent type of ATL
5	F	60.0	Southern	Other disease	Unknown	None	9.12	340	14	192	5100	Sm	6.0
6	F	71.9	Southern	Multiphasic screening	None	None	10.60	1320	2	199	4000	Sm	29.8
7	F	59.5	Southern	Multiphasic screening	None	None	21.90	635	4.5	188	4100	Sm	12.0
8	F	74.0	Southern	Other disease	Unknown	Gallbladder cancer	10.11	1110	2	240	2700	Sm	26.8
9	F	54.1	Southern	Other disease	Unknown	None	18.85	971	2	198	5660	Sm	29.0
10	F	43.3	Southern	Pregnancy	ATL	None	13.90	372	1	ND	5400	Sm	64.4
11	F	62.2	Southern	Other disease	Unknown	Eye disease	6.86	1560	ND	508	12100	Sm	6.0
12	M	57.6	Southern	Other disease	Unknown	None	7.67	ND	2	234	5500	Sm	15.4
13	F	41.0	Metropolitan	Pregnancy	None	None	12.14	349	2.5	189	7690	Sm	12.2
14	M	66.1	Southern	Other disease	None	Prostatitis	28.58	2660	0	158	8500	Sm	2.8

Case no.	Demographic characteristics						Baseline clinical and biologic values					ATL development
Case no.	Sex	Age, y	Place of birth	First opportunity for HTLV-1 testing	Family history of HTLV-1–related disease	Comorbidity at enrollment	HTLV-1 VL, copies/100 PBMCs	sIL-2R, U/mL	Abnormal lymphocytes, percentage	LDH, IU/L	WBC, ×10³/mm³	Clinical type	Duration from enrollment, mo
Progression to aggressive type of ATL
1	M	79.9	Southern	ATL family	ATL	None	5.47	479	2	157	4200	Acute	7.4
2	F	70.3	Southern	ATL family	ATL	None	4.73	904	0	365	9130	Acute	38.6
3	M	71.9	Southern	Other disease	None	Skin disease	4.17	1450	0	351	5140	Lymph	4.6
4	F	75.8	Southern	Unknown	Unknown	None	10.52	2080	3	308	3600	Lymph	30.6
Progression to indolent type of ATL
5	F	60.0	Southern	Other disease	Unknown	None	9.12	340	14	192	5100	Sm	6.0
6	F	71.9	Southern	Multiphasic screening	None	None	10.60	1320	2	199	4000	Sm	29.8
7	F	59.5	Southern	Multiphasic screening	None	None	21.90	635	4.5	188	4100	Sm	12.0
8	F	74.0	Southern	Other disease	Unknown	Gallbladder cancer	10.11	1110	2	240	2700	Sm	26.8
9	F	54.1	Southern	Other disease	Unknown	None	18.85	971	2	198	5660	Sm	29.0
10	F	43.3	Southern	Pregnancy	ATL	None	13.90	372	1	ND	5400	Sm	64.4
11	F	62.2	Southern	Other disease	Unknown	Eye disease	6.86	1560	ND	508	12100	Sm	6.0
12	M	57.6	Southern	Other disease	Unknown	None	7.67	ND	2	234	5500	Sm	15.4
13	F	41.0	Metropolitan	Pregnancy	None	None	12.14	349	2.5	189	7690	Sm	12.2
14	M	66.1	Southern	Other disease	None	Prostatitis	28.58	2660	0	158	8500	Sm	2.8

ATL indicates adult T-cell leukemia; HTLV-1, human T-cell leukemia virus type 1;VL, HTLV-1 proviral load; PBMCs, peripheral blood mononuclear cells; sIL-2R, soluble interleukin-2 receptor; LDH, lactate dehydrogenase; WBC, white blood cell count; Sm, smoldering type; and ND, not done.

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