Table 1

Experimental knob A peptides and corresponding properties

Peptide sequencePropertyNet charge
GPRVVERC Mimics native sequence through seventh residue +1 
GPRVVAAC Mimics native sequence minus additional charged residues +1 
GPRPAAC Stabilized backbone +1 
GPRPFPAC Stabilized backbone +1 
GPRPPERC Stabilized backbone and additional charged residues +1 
GPSPAAC Negative control; known dysfibinrogen mutant 
Peptide sequencePropertyNet charge
GPRVVERC Mimics native sequence through seventh residue +1 
GPRVVAAC Mimics native sequence minus additional charged residues +1 
GPRPAAC Stabilized backbone +1 
GPRPFPAC Stabilized backbone +1 
GPRPPERC Stabilized backbone and additional charged residues +1 
GPSPAAC Negative control; known dysfibinrogen mutant 

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