Table 1 Sickle cell patient... | American Society of Hematology

Table 1

Sickle cell patient characteristics and laboratory values

Patient no.	Age, y/sex	Genotype	Hydroxyurea	Leukocytes, 10³/μL	Platelets, 10³/μL	Reticulocytes, 10⁶/μL	Hematocrit, %	LDH, units/L	ADAMTS13,* %
Patient no.	Age, y/sex	Genotype	Hydroxyurea	Leukocytes, 10³/μL	Platelets, 10³/μL	Reticulocytes, 10⁶/μL	Hematocrit, %	LDH, units/L	Activity	Antigen	Specific activity
1	50/F	SS	Yes	6.62	284	175	29	381	—	—	—
				5.23	228	125	28	225	60	72	84
				10.52	326	82	25	342	94	78	120
2	34/M	SS	Yes†	17.94	576	205	25	465	63	115	55
				17.40	653	170	25	491	137	119	115
3	45/M	SS	Yes	6.79	554	311	24	282
				8.71	317	211	29	514	99	99	100
4	49/M	SS	Yes	5.48	150	244	25	394	112	116	97
5	25/M	SS	Yes†	12.74	359	259	26	210	86	113	76
6	26/F	SS	No	9.92	368	294	26	485	106	108	98
7	23/F	SS	No	16.26	413	447	23	378	87	112	78
8	48/M	SS	Yes†	11.21	323	271	23	418	100	132	76
9	24/F	SS	Yes	7.16	366	313	28	250	94	103	91
10	29/M	Sβ⁰	Yes	9.44	310	270	31	395	104	108	96
				11.00	464	280	34	437	144	119	120
11	24/M	SC	Yes†	6.58	426	124	33	215	198	139	142
				6.95	388	111	30	210	159	124	128
12	19/F	Sβ⁺	No	11.66	443	326	22	235	113	119	95
13	21/F	Sβ⁺	No	4.84	401	192	33	220	110	128	86
Normal range				4.3-10	150-400	20-65	36-45	80-190	100	100	100

Patient no.	Age, y/sex	Genotype	Hydroxyurea	Leukocytes, 10³/μL	Platelets, 10³/μL	Reticulocytes, 10⁶/μL	Hematocrit, %	LDH, units/L	ADAMTS13,* %
Patient no.	Age, y/sex	Genotype	Hydroxyurea	Leukocytes, 10³/μL	Platelets, 10³/μL	Reticulocytes, 10⁶/μL	Hematocrit, %	LDH, units/L	Activity	Antigen	Specific activity
1	50/F	SS	Yes	6.62	284	175	29	381	—	—	—
				5.23	228	125	28	225	60	72	84
				10.52	326	82	25	342	94	78	120
2	34/M	SS	Yes†	17.94	576	205	25	465	63	115	55
				17.40	653	170	25	491	137	119	115
3	45/M	SS	Yes	6.79	554	311	24	282
				8.71	317	211	29	514	99	99	100
4	49/M	SS	Yes	5.48	150	244	25	394	112	116	97
5	25/M	SS	Yes†	12.74	359	259	26	210	86	113	76
6	26/F	SS	No	9.92	368	294	26	485	106	108	98
7	23/F	SS	No	16.26	413	447	23	378	87	112	78
8	48/M	SS	Yes†	11.21	323	271	23	418	100	132	76
9	24/F	SS	Yes	7.16	366	313	28	250	94	103	91
10	29/M	Sβ⁰	Yes	9.44	310	270	31	395	104	108	96
				11.00	464	280	34	437	144	119	120
11	24/M	SC	Yes†	6.58	426	124	33	215	198	139	142
				6.95	388	111	30	210	159	124	128
12	19/F	Sβ⁺	No	11.66	443	326	22	235	113	119	95
13	21/F	Sβ⁺	No	4.84	401	192	33	220	110	128	86
Normal range				4.3-10	150-400	20-65	36-45	80-190	100	100	100

Patients 1,2,3,10, and 11 were tested more than once.

LDH indicates lactate dehydrogenase in plasma; SS, homozygous sickle disease; SC, hemoglobin SC disease; Sβ⁺, sickle β (+) thalassemia; and Sβ⁰, sickle β (0) thalassemia.

Values were expressed relative to pooled normal plasma.

†

Patient reported intermittent noncompliance.

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