Table 3 Clinical and therapeutic... | American Society of Hematology

Table 3

Clinical and therapeutic predictors of survival in ECD (multivariate survival analysis using the Cox proportional hazard model)

Variable	Univariate analysis (P)	Cox multivariate survival analysis*
Variable	Univariate analysis (P)	HR (95% CI)	P
Sex	.55
Cardiovascular involvement	.57
CNS involvement	.10	2.51 (1.28-5.52)	.006
Hypophyseal involvement	.93
Paranasal sinus involvement	.54
Maxillary involvement	.23
Xanthelasma	.98
Orbital involvement	.57
Pulmonary involvement	.21
Retroperitoneal involvement	.31
Adrenal involvement	.53
Treatment with interferons†	.03	0.32 (0.14-0.70)	.006

Variable	Univariate analysis (P)	Cox multivariate survival analysis*
Variable	Univariate analysis (P)	HR (95% CI)	P
Sex	.55
Cardiovascular involvement	.57
CNS involvement	.10	2.51 (1.28-5.52)	.006
Hypophyseal involvement	.93
Paranasal sinus involvement	.54
Maxillary involvement	.23
Xanthelasma	.98
Orbital involvement	.57
Pulmonary involvement	.21
Retroperitoneal involvement	.31
Adrenal involvement	.53
Treatment with interferons†	.03	0.32 (0.14-0.70)	.006

P < .20 in univariate analysis were entered in the multivariate model.

Adjusted for the age at compilation (quartiles of the distribution) and the use of corticosteroids or of any other immunosuppressive drugs.

Treatment with interferon-α and/or PEGylated-interferon-α.