Short-term radioprotection by limiting injection of FL cells
| No. of cells injected/mouse . | No. of mice surviving until week 4 after transplantation . | |
|---|---|---|
| TGF-β1+/+ . | TGF-β1−/− . | |
| 10 × 106 | 5/5 | 3/5 |
| 5 × 106 | 5/5 | 2/5 |
| 1 × 106 | 4/5 | 0/5 |
| 0.5 × 106 | 3/5 | 0/5 |
| No. of cells injected/mouse . | No. of mice surviving until week 4 after transplantation . | |
|---|---|---|
| TGF-β1+/+ . | TGF-β1−/− . | |
| 10 × 106 | 5/5 | 3/5 |
| 5 × 106 | 5/5 | 2/5 |
| 1 × 106 | 4/5 | 0/5 |
| 0.5 × 106 | 3/5 | 0/5 |
Freshly isolated total FL cells were engrafted to lethally irradiated recipient mice at the concentrations indicated. Values represent the number of living mice, 4 weeks after transplantation, of 5 animals injected per cell dose and per genotype.