Table 8

Summary of results for splenectomy in patients with LGL leukemia

No. of patientsIndicationResponseCommentsReference (year)
Neutropenia 2/4 1 patient died; 2 sustained response 91 (1987) 
5/8 — 59 (1994) 
Thrombocytopenia 1/1 Normalization of platelet count; death of patient 2 years later 92 (1991) 
AIHA 1/1 Normalization of Hb level 53 (1998) 
No — 93 (1998) 
15 Splenomegaly; cytopenias 13/15 13/15 sustained response; 2 patients died 94 (2008) 
12 5/12 — 13 (2009) 
13 Splenomegaly; cytopenias 4/13 — 12 (2010) 
Total (n = 55)  31/55 (56%)   
No. of patientsIndicationResponseCommentsReference (year)
Neutropenia 2/4 1 patient died; 2 sustained response 91 (1987) 
5/8 — 59 (1994) 
Thrombocytopenia 1/1 Normalization of platelet count; death of patient 2 years later 92 (1991) 
AIHA 1/1 Normalization of Hb level 53 (1998) 
No — 93 (1998) 
15 Splenomegaly; cytopenias 13/15 13/15 sustained response; 2 patients died 94 (2008) 
12 5/12 — 13 (2009) 
13 Splenomegaly; cytopenias 4/13 — 12 (2010) 
Total (n = 55)  31/55 (56%)   

AIHA indicates autoimmune hemolytic anemia; —, not applicable; and Hb, hemoglobin.

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