Patients with PDGFRA point mutations
ID . | Clinical diagnosis . | Mutation . | Polymorphism . | PDGFRA overexpression . | Sex . | Age, y . | Eosinophil count, /μL . |
---|---|---|---|---|---|---|---|
1 | HES | R481G | P567P | Yes | Male | 76 | 276* |
2 | HES | I562M, H570R | S478P, A603A | Yes | Male | 76 | 810* |
3 | HES and CLL | H650Q, R748G | P567P | Yes | Female | 65 | 4320 |
4 | HES | L705P | P567P | Yes | Male | 70 | 5334 |
5 | HES | Y849S | P567P, V824V | No | Male | 67 | NA |
6 | HES | Y849S, L507P | None | No | Male | 25 | NA |
7 | HES | N659S | P567P | No | Female | 45 | 204* |
ID . | Clinical diagnosis . | Mutation . | Polymorphism . | PDGFRA overexpression . | Sex . | Age, y . | Eosinophil count, /μL . |
---|---|---|---|---|---|---|---|
1 | HES | R481G | P567P | Yes | Male | 76 | 276* |
2 | HES | I562M, H570R | S478P, A603A | Yes | Male | 76 | 810* |
3 | HES and CLL | H650Q, R748G | P567P | Yes | Female | 65 | 4320 |
4 | HES | L705P | P567P | Yes | Male | 70 | 5334 |
5 | HES | Y849S | P567P, V824V | No | Male | 67 | NA |
6 | HES | Y849S, L507P | None | No | Male | 25 | NA |
7 | HES | N659S | P567P | No | Female | 45 | 204* |
HES indicates idiopathic hypereosinophilic syndrome; CLL, chronic lymphocytic leukemia; and NA, not available.
During treatment with prednisone and cyclophosphamide.