Tryptase and MITF are coexpressed in patients with systemic mastocytosis and c-KIT mutations
| Patient no. . | Diagnosis . | . | Staining . | |
|---|---|---|---|---|
| Tryptase . | MITF . | |||
| 1 | Indolent systemic mastocytosis | D816V | ++ | + |
| 2 | Indolent systemic mastocytosis | D816V | ++ | + |
| 3 | Indolent systemic mastocytosis | D816V | ++ | + |
| 4 | Indolent systemic mastocytosis | D816V | ++ | + |
| 5 | Indolent systemic mastocytosis | D816V | ++ | + |
| 6 | Indolent systemic mastocytosis | D816V | ++ | + |
| 7 | Indolent systemic mastocytosis | D816V | ++ | + |
| 8 | Indolent systemic mastocytosis | D816V | ++ | + |
| 9 | Systemic mastocytosis | F522C | ++ | + |
| 10 | Aggressive systemic mastocytosis | D816Y | ++ | − |
| 11 | Aplastic anemia | NT | ++ | − |
| 12 | Aplastic anemia | NT | ++ | − |
| 13 | Aplastic anemia | NT | ++ | − |
| 14 | Aplastic anemia | NT | ++ | − |
| 15 | Aplastic anemia | NT | ++ | − |
| 16 | Aplastic anemia | NT | ++ | − |
| 17 | Aplastic anemia | NT | ++ | − |
| 18 | Fanconi anemia | NT | ++ | − |
| 19 | Acute lymphoblastic leukemia | NT | ++ | − |
| 20 | Hemophagocytic lymphohistiocytosis | NT | ++ | − |
| Patient no. . | Diagnosis . | . | Staining . | |
|---|---|---|---|---|
| Tryptase . | MITF . | |||
| 1 | Indolent systemic mastocytosis | D816V | ++ | + |
| 2 | Indolent systemic mastocytosis | D816V | ++ | + |
| 3 | Indolent systemic mastocytosis | D816V | ++ | + |
| 4 | Indolent systemic mastocytosis | D816V | ++ | + |
| 5 | Indolent systemic mastocytosis | D816V | ++ | + |
| 6 | Indolent systemic mastocytosis | D816V | ++ | + |
| 7 | Indolent systemic mastocytosis | D816V | ++ | + |
| 8 | Indolent systemic mastocytosis | D816V | ++ | + |
| 9 | Systemic mastocytosis | F522C | ++ | + |
| 10 | Aggressive systemic mastocytosis | D816Y | ++ | − |
| 11 | Aplastic anemia | NT | ++ | − |
| 12 | Aplastic anemia | NT | ++ | − |
| 13 | Aplastic anemia | NT | ++ | − |
| 14 | Aplastic anemia | NT | ++ | − |
| 15 | Aplastic anemia | NT | ++ | − |
| 16 | Aplastic anemia | NT | ++ | − |
| 17 | Aplastic anemia | NT | ++ | − |
| 18 | Fanconi anemia | NT | ++ | − |
| 19 | Acute lymphoblastic leukemia | NT | ++ | − |
| 20 | Hemophagocytic lymphohistiocytosis | NT | ++ | − |
+ indicates positive staining ++, strongly positive staining −, no detectable staining and — NT, not tested.