Baseline characteristics at sea level (SL1) by sex
| Variable . | Females . | Males . | ||||||
|---|---|---|---|---|---|---|---|---|
| n . | Mean . | Median . | 1st-3rd quartile . | n . | Mean . | Median . | 1st-3rd quartile . | |
| Age, y | 10 | 35.5 | 33.0 | 26.0-40.0 | 31 | 41.1 | 40.0 | 33.0-48.0 |
| Weight, kg | 10 | 56.6 | 55.5 | 52.0-57.0 | 31 | 74.3 | 74.0 | 68.0-80.0 |
| BMI, kg/m2 | 10 | 20.9 | 20.3 | 19.7-21.0 | 31 | 23.6 | 23.5 | 21.8-25.3 |
| Hematocrit, % | 10 | 38.1 | 38.4 | 34.0-40.9 | 31 | 43.5 | 43.8 | 41.5-45.3 |
| Hepcidin, ng/mL | 10 | 27.0 | 22.8 | 15.3-35.1 | 30 | 57.0 | 67.0 | 40.3-93.5 |
| Erythropoietin, mU/mL | 10 | 13.0 | 11.9 | 9.4-17.8 | 30 | 11.1 | 10.7 | 8.8-13.7 |
| Serum iron, μg/dL | 9 | 75.5 | 83.0 | 67.0-87.0 | 30 | 75.9 | 73.5 | 63.0-95.0 |
| Transferrin, mg/dL | 8 | 262.5 | 245.0 | 221.5-311.5 | 29 | 237.8 | 242.0 | 218.0-259.0 |
| Transferrin saturation, % | 8 | 21.8 | 23.0 | 15.9-28.4 | 29 | 22.9 | 22.4 | 18.7-29.0 |
| Ferritin, ng/mL | 10 | 40.1 | 34.5 | 31.0-69.0 | 30 | 139.9 | 139.0 | 104.0-209.0 |
| Soluble transferrin receptor, pmol/mL | 10 | 20.5 | 19.2 | 17.4-23.4 | 29 | 21.2 | 21.7 | 17.2-24.0 |
| GDF15, pg/mL | 10 | 332.9 | 368.4 | 187.3-444.7 | 28 | 340.8 | 386.8 | 223.4-494.2 |
| IL-6, pg/mL | 10 | 14.7 | 16.2 | 9.2-18.9 | 30 | 19.7 | 16.8 | 12.8-29.0 |
| Variable . | Females . | Males . | ||||||
|---|---|---|---|---|---|---|---|---|
| n . | Mean . | Median . | 1st-3rd quartile . | n . | Mean . | Median . | 1st-3rd quartile . | |
| Age, y | 10 | 35.5 | 33.0 | 26.0-40.0 | 31 | 41.1 | 40.0 | 33.0-48.0 |
| Weight, kg | 10 | 56.6 | 55.5 | 52.0-57.0 | 31 | 74.3 | 74.0 | 68.0-80.0 |
| BMI, kg/m2 | 10 | 20.9 | 20.3 | 19.7-21.0 | 31 | 23.6 | 23.5 | 21.8-25.3 |
| Hematocrit, % | 10 | 38.1 | 38.4 | 34.0-40.9 | 31 | 43.5 | 43.8 | 41.5-45.3 |
| Hepcidin, ng/mL | 10 | 27.0 | 22.8 | 15.3-35.1 | 30 | 57.0 | 67.0 | 40.3-93.5 |
| Erythropoietin, mU/mL | 10 | 13.0 | 11.9 | 9.4-17.8 | 30 | 11.1 | 10.7 | 8.8-13.7 |
| Serum iron, μg/dL | 9 | 75.5 | 83.0 | 67.0-87.0 | 30 | 75.9 | 73.5 | 63.0-95.0 |
| Transferrin, mg/dL | 8 | 262.5 | 245.0 | 221.5-311.5 | 29 | 237.8 | 242.0 | 218.0-259.0 |
| Transferrin saturation, % | 8 | 21.8 | 23.0 | 15.9-28.4 | 29 | 22.9 | 22.4 | 18.7-29.0 |
| Ferritin, ng/mL | 10 | 40.1 | 34.5 | 31.0-69.0 | 30 | 139.9 | 139.0 | 104.0-209.0 |
| Soluble transferrin receptor, pmol/mL | 10 | 20.5 | 19.2 | 17.4-23.4 | 29 | 21.2 | 21.7 | 17.2-24.0 |
| GDF15, pg/mL | 10 | 332.9 | 368.4 | 187.3-444.7 | 28 | 340.8 | 386.8 | 223.4-494.2 |
| IL-6, pg/mL | 10 | 14.7 | 16.2 | 9.2-18.9 | 30 | 19.7 | 16.8 | 12.8-29.0 |
Geometric mean values are given for mean for all parameters except age, weight, and BMI.