Effect of acute hypoxia (Namche) on the relevant parameters by group A and group B: 16 and 40 hours of exposure to altitude, respectively
| Variable . | Group A . | Group B . | ||||||
|---|---|---|---|---|---|---|---|---|
| n . | Sea level, mean . | Namche, mean . | P . | n . | Sea level, mean . | Namche, mean . | P . | |
| Hematocrit, % | 20 | 41.7 | 45.6 | < .0001 | 21 | 42.5 | 43.0 | .5826 |
| Hepcidin,* ng/mL | 18 | 50.4 | 38.5 | .0869 | 21 | 48.9 | 28.5 | .0003 |
| Erythropoietin, mU/mL | 20 | 11.8 | 35.5 | < .0001 | 20 | 11.3 | 30.0 | < .0001 |
| Serum iron, μg/dL | 19 | 80.6 | 89.1 | .3014 | 20 | 70.8 | 116.7 | < .0001 |
| Transferrin, mg/dL | 18 | 244.7 | 275.9 | .0007 | 19 | 239.8 | 270.4 | .0004 |
| Transferrin saturation, % | 18 | 24.1 | 22.9 | .6515 | 19 | 21.3 | 30.6 | .0002 |
| Ferritin, ng/mL | 19 | 116.8 | 84.8 | < .0001 | 21 | 90.9 | 76.7 | .0035 |
| Soluble transferrin receptor, pmol/mL | 19 | 20.3 | 23.3 | .1777 | 20 | 21.8 | 23.6 | .4084 |
| GDF15, pg/mL | 19 | 361.4 | 528.5 | < .0001 | 19 | 317.4 | 473.4 | < .0001 |
| IL-6,* pg/mL | 18 | 20.2 | 25.2 | .2107 | 21 | 16.0 | 25.6 | .0035 |
| Variable . | Group A . | Group B . | ||||||
|---|---|---|---|---|---|---|---|---|
| n . | Sea level, mean . | Namche, mean . | P . | n . | Sea level, mean . | Namche, mean . | P . | |
| Hematocrit, % | 20 | 41.7 | 45.6 | < .0001 | 21 | 42.5 | 43.0 | .5826 |
| Hepcidin,* ng/mL | 18 | 50.4 | 38.5 | .0869 | 21 | 48.9 | 28.5 | .0003 |
| Erythropoietin, mU/mL | 20 | 11.8 | 35.5 | < .0001 | 20 | 11.3 | 30.0 | < .0001 |
| Serum iron, μg/dL | 19 | 80.6 | 89.1 | .3014 | 20 | 70.8 | 116.7 | < .0001 |
| Transferrin, mg/dL | 18 | 244.7 | 275.9 | .0007 | 19 | 239.8 | 270.4 | .0004 |
| Transferrin saturation, % | 18 | 24.1 | 22.9 | .6515 | 19 | 21.3 | 30.6 | .0002 |
| Ferritin, ng/mL | 19 | 116.8 | 84.8 | < .0001 | 21 | 90.9 | 76.7 | .0035 |
| Soluble transferrin receptor, pmol/mL | 19 | 20.3 | 23.3 | .1777 | 20 | 21.8 | 23.6 | .4084 |
| GDF15, pg/mL | 19 | 361.4 | 528.5 | < .0001 | 19 | 317.4 | 473.4 | < .0001 |
| IL-6,* pg/mL | 18 | 20.2 | 25.2 | .2107 | 21 | 16.0 | 25.6 | .0035 |
Geometric mean values are given for mean.
Two subjects in group A were excluded from the analysis of hepcidin and IL-6 because of upper airway infection.