rsTreg reconstitution
. | rsTreg numbers, ×106 . | |||
---|---|---|---|---|
Day 7 . | Day 15 . | Day 30 . | Day 60 . | |
Tallo+rsTreg | 0.45 ± 0.11 | 1.72 ± 0.23 | 0.64 ± 0.12 | 0.09 ± 0.01 |
Percentage of rsTreg/CD4 | n = 5 | n = 5 | n = 5 | n = 4 |
Tallo+rsTreg | 32.26 ± 4.32 | 31.88 ± 0.67 | 12.26 ± 2.30 | 8.69 ± 1.90 |
. | rsTreg numbers, ×106 . | |||
---|---|---|---|---|
Day 7 . | Day 15 . | Day 30 . | Day 60 . | |
Tallo+rsTreg | 0.45 ± 0.11 | 1.72 ± 0.23 | 0.64 ± 0.12 | 0.09 ± 0.01 |
Percentage of rsTreg/CD4 | n = 5 | n = 5 | n = 5 | n = 4 |
Tallo+rsTreg | 32.26 ± 4.32 | 31.88 ± 0.67 | 12.26 ± 2.30 | 8.69 ± 1.90 |
[BALB/c × C57BL/6]F1 recipient mice were lethally irradiated and then grafted with 3 × 106 CD3ε−/− BM cells and 3 × 106 allogeneic Ly5.1+ C57BL/6 T cells and with 3 × 106 Thy1.1+ rsTreg (Tallo+rsTreg). Immune reconstitution of rsTreg was evaluated in the spleen 7, 15, 30, and 60 days after transplantation.