Relationship between cytogenetics and age, morphology and immunophenotype in MPAL
| Cytogenetics . | Cases, % . | M/F . | Ch/Ad . | ALL/AML/AUL* . | B + My . | T + My . | B + T . | B + T + My . |
|---|---|---|---|---|---|---|---|---|
| Ph+/BCR-ABL | 15 | 8/7 | 3/12 | 6/6/3 | 11 | 2 | 1 | 1 |
| 11q23 | 6 | 3/3 | 3/3 | 2/3/0 | 5 | 1 | 0 | 0 |
| Complex | 24 | 16/8 | 7/17 | 9/10/3 | 11 | 12 | 1 | 0 |
| Others† | 21 | 7/14 | 11/10 | 10/7/4 | 12 | 8 | 1 | 0 |
| Normal | 10 | 7/3 | 4/6 | 6/4/0 | 4 | 4 | 1 | 1 |
| Cytogenetics . | Cases, % . | M/F . | Ch/Ad . | ALL/AML/AUL* . | B + My . | T + My . | B + T . | B + T + My . |
|---|---|---|---|---|---|---|---|---|
| Ph+/BCR-ABL | 15 | 8/7 | 3/12 | 6/6/3 | 11 | 2 | 1 | 1 |
| 11q23 | 6 | 3/3 | 3/3 | 2/3/0 | 5 | 1 | 0 | 0 |
| Complex | 24 | 16/8 | 7/17 | 9/10/3 | 11 | 12 | 1 | 0 |
| Others† | 21 | 7/14 | 11/10 | 10/7/4 | 12 | 8 | 1 | 0 |
| Normal | 10 | 7/3 | 4/6 | 6/4/0 | 4 | 4 | 1 | 1 |
No significant differences between cytogenetic groups and sex (P = .2), age (P = .3), morphology (P = .8), and phenotype (P = .2).
MPAL indicates mixed-phenotype acute leukemia; M, male; F, female; Ch, child; Ad, adult; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; AUL, undifferentiated acute leukemia.
Morphology review was not possible in 8 cases.
Included 2 cases with a hyperdiploid karyotype.