Table 1 TEG-derived values for global... | American Society of Hematology

Table 1

TEG-derived values for global whole blood coagulation parameters of transgenic mouse lines

	R (minutes)	K (minutes)	A (°)	MA (mm)	n
WT
0	7.3 ± 2.1	3.3 ± 1.2	52.4 ± 3.4	64.5 ± 2.1	9
12 hours	19.8 ± 3.5*	11.7 ± 2.5*	18.6 ± 3.7*	30.8 ± 4.1*	6
PC^−/−PC(tg4)/TF^−/−hTF(tg)
0	21.3 ± 1.9*	8.9 ± 1.2*	25.3 ± 2.2*	56.3 ± 3.0*	6
12 hours	> 120†	0†	0†	0†	6
PC^−/−PC(tg785)	13.0 ± 3.2*	4.8 ± 2.0	48.3 ± 4.7	65.0 ± 3.2	8
TF^−/−hTF(tg)	19.9 ± 2.1*	7.4 ± 1.1*	31.5 ± 3.2*	63.8 ± 4.6	7
Fg^−/−	> 120‡	0‡	0‡	0‡	6
Fg^+/−	4.7 ± 0.9	1.8 ± 0.3	64.4 ± 3.3*	61.3 ± 1.5	5

	R (minutes)	K (minutes)	A (°)	MA (mm)	n
WT
0	7.3 ± 2.1	3.3 ± 1.2	52.4 ± 3.4	64.5 ± 2.1	9
12 hours	19.8 ± 3.5*	11.7 ± 2.5*	18.6 ± 3.7*	30.8 ± 4.1*	6
PC^−/−PC(tg4)/TF^−/−hTF(tg)
0	21.3 ± 1.9*	8.9 ± 1.2*	25.3 ± 2.2*	56.3 ± 3.0*	6
12 hours	> 120†	0†	0†	0†	6
PC^−/−PC(tg785)	13.0 ± 3.2*	4.8 ± 2.0	48.3 ± 4.7	65.0 ± 3.2	8
TF^−/−hTF(tg)	19.9 ± 2.1*	7.4 ± 1.1*	31.5 ± 3.2*	63.8 ± 4.6	7
Fg^−/−	> 120‡	0‡	0‡	0‡	6
Fg^+/−	4.7 ± 0.9	1.8 ± 0.3	64.4 ± 3.3*	61.3 ± 1.5	5

P < .05 from WT mice.

P < .05 from all mice tested, except when compared with Fg^−/−.

P < .05 from all mice tested, except when compared with PC^−/−(tg4)/hTF^−/−(tg) at 12 hours post-LPS.