Table 1

Embryonic lethality of due to deletion of Mfrn1

Embryos/pups≤ E9.5 (n = 37)≥ E11.5 (n = 41)Newborn (n = 64)
Mfrn1+/+ 10 10 20 
Mfrn1+/− 19 22 44 
Mfrn1−/− 
Not determined (necrotic embryos) 
Embryos/pups≤ E9.5 (n = 37)≥ E11.5 (n = 41)Newborn (n = 64)
Mfrn1+/+ 10 10 20 
Mfrn1+/− 19 22 44 
Mfrn1−/− 
Not determined (necrotic embryos) 

Mice (Mfrn1+/−) heterozygous for a Mfrn1 deletion were intercrossed and the progeny were genotyped.

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