Most abundant angiogenic factors shared between HUVEC-derived HCMV VR1814 and NHDF-derived HCMV AD169 secretomes*
| Protein . | Mock secretome NHDF average intensity ± SD . | Infected secretome NHDF average intensity ± SD . | Fold change . | Mock secretome HUVEC average intensity ± SD . | Infected secretome HUVEC average intensity ± SD . | Fold change . |
|---|---|---|---|---|---|---|
| IL-6 | 1037 ± 447 | 24617 ± 2641 | 23.7 | 6769 ± 395 | 43424 ± 4339 | 6.4 |
| GM-CSF | 280 ± 5 | 5661 ± 831 | 20.2 | 1422 ± 102 | 4384 ± 507 | 3.1 |
| IL-8 | 234 ± 162 | 1787 ± 400 | 7.6 | 865 ± 63 | 1507 ± 112 | 1.7 |
| MIP-1β | 435 ± 89 | 7058 ± 238 | 16.2 | 982 ± 42 | 3580 ± 947 | 3.6 |
| MCP-3 | 26 ± 9 | 102 ± 22 | 3.9 | 8184 ± 963 | 28152 ± 3962 | 3.4 |
| MIP-3α | 170 ± 12 | 896 ± 92 | 5.2 | 5815 ± 369 | 47202 ± 6571 | 8.1 |
| I-TAC | 251 ± 189 | 1115 ± 227 | 4.4 | 2436 ± 219 | 7626 ± 996 | 3.1 |
| Protein . | Mock secretome NHDF average intensity ± SD . | Infected secretome NHDF average intensity ± SD . | Fold change . | Mock secretome HUVEC average intensity ± SD . | Infected secretome HUVEC average intensity ± SD . | Fold change . |
|---|---|---|---|---|---|---|
| IL-6 | 1037 ± 447 | 24617 ± 2641 | 23.7 | 6769 ± 395 | 43424 ± 4339 | 6.4 |
| GM-CSF | 280 ± 5 | 5661 ± 831 | 20.2 | 1422 ± 102 | 4384 ± 507 | 3.1 |
| IL-8 | 234 ± 162 | 1787 ± 400 | 7.6 | 865 ± 63 | 1507 ± 112 | 1.7 |
| MIP-1β | 435 ± 89 | 7058 ± 238 | 16.2 | 982 ± 42 | 3580 ± 947 | 3.6 |
| MCP-3 | 26 ± 9 | 102 ± 22 | 3.9 | 8184 ± 963 | 28152 ± 3962 | 3.4 |
| MIP-3α | 170 ± 12 | 896 ± 92 | 5.2 | 5815 ± 369 | 47202 ± 6571 | 8.1 |
| I-TAC | 251 ± 189 | 1115 ± 227 | 4.4 | 2436 ± 219 | 7626 ± 996 | 3.1 |
Factor values (in arbitrary units) were determined by RayBiotech protein array.