Table 2 Candidate variants and their... | American Society of Hematology

Table 2

Candidate variants and their association with incident VT in the HVH study

CHR	SNP	Gene	Variant*	Substitution	P	MAF	OR† (95% CI)
6	rs1039084	STXBP5 (exon)	A → G	N → S	.0052	0.46	0.78 (0.65-0.93)
8	rs2726953	SCARA5 (intron)	C → T		.81	0.31	0.98 (0.81-1.18)
9	rs687621	ABO (intron)	T → C		.0000024	0.34	1.52 (1.28-1.80)
12	rs1063856	VWF (exon)	A → G	T → A	.036	0.37	1.20 (1.01-1.42)
12	rs4981022	STAB2 (intron)	T → C		.83	0.37	0.97 (0.74-1.27)
12	rs7978987	STX2 (intron)	G → A		.94	0.32	1.01 (0.83-1.22)
14	rs10133762	TC2N (intron)	G → T		.81	0.43	1.02 (0.87-1.20)
19	rs868875	CLEC4M (3′ UTR)	A → G		.77	0.23	1.07 (0.67-1.72)

CHR	SNP	Gene	Variant*	Substitution	P	MAF	OR† (95% CI)
6	rs1039084	STXBP5 (exon)	A → G	N → S	.0052	0.46	0.78 (0.65-0.93)
8	rs2726953	SCARA5 (intron)	C → T		.81	0.31	0.98 (0.81-1.18)
9	rs687621	ABO (intron)	T → C		.0000024	0.34	1.52 (1.28-1.80)
12	rs1063856	VWF (exon)	A → G	T → A	.036	0.37	1.20 (1.01-1.42)
12	rs4981022	STAB2 (intron)	T → C		.83	0.37	0.97 (0.74-1.27)
12	rs7978987	STX2 (intron)	G → A		.94	0.32	1.01 (0.83-1.22)
14	rs10133762	TC2N (intron)	G → T		.81	0.43	1.02 (0.87-1.20)
19	rs868875	CLEC4M (3′ UTR)	A → G		.77	0.23	1.07 (0.67-1.72)

VT indicates venous thrombosis; HVH, Heart and Vascular Health; CHR, chromosome; MAF, minor allele frequency; OR, odds ratio; and CI, confidence interval.

Change in nucleotide from common to variant allele.

†

Relative risk associated with each additional copy of the variant allele.

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