Expressed miRNAs mapping to copy number alterations
Chromosome . | miR . | Bp start . | Bp end . | P* . |
---|---|---|---|---|
Chr 1 (amplification) | miR-30e | 40 s683 565 | 40 683 656 | .08 |
miR-30c-1 | 40 686 494 | 40 686 582 | NA | |
miR-101-1 | 65 296 705 | 65 296 779 | .0008 | |
miR-186 | 71 305 902 | 71 305 987 | .32 | |
miR-9-1 | 154 656 757 | 154 656 845 | .26 | |
miR-181b-1 | 197 094 625 | 197 094 734 | .0001 | |
miR-181a-1 | 197 094 796 | 197 094 905 | .0084 | |
miR-29c | 206 041 820 | 206 041 907 | NA | |
Chr 3 (deletion) | miR-128-2 | 35 760 972 | 35 761 055 | .0001 |
miR-26a-1 | 37 985 899 | 37 985 975 | .0001 | |
miR-138-1 | 44 130 708 | 44 130 806 | .11 | |
miR-425 | 49 032 585 | 49 032 671 | NA | |
miR-191 | 49 033 055 | 49 033 146 | .95 | |
let-7g | 52 277 334 | 52 277 417 | .0001 | |
miR-15b | 161 605 070 | 161 605 167 | NA | |
miR-16-2 | 161 605 227 | 161 605 307 | .042 | |
miR-28 | 189 889 263 | 189 889 348 | NA | |
Chr 5 (deletion) | miR-9-2 | 87 998 427 | 87 998 513 | NA |
miR-886 | 135 444 076 | 135 444 196 | NA | |
miR-143 | 148 788 674 | 148 788 779 | NA | |
miR-378 | 149 092 581 | 149 092 646 | NA | |
miR-146a | 159 844 937 | 159 845 035 | .0008 | |
miR-103-1 | 167 920 487 | 167 920 548 | NA | |
miR-340 | 179 374 909 | 179 375 003 | .0001 | |
Chr 6 (amplification) | miR-30a | 72 169 975 | 72 170 045 | NA |
Chr 7 (deletion) | miR-148a | 25 956 064 | 25 956 131 | .0001 |
miR-25 | 99 529 119 | 99 529 202 | NA | |
miR-93 | 99 529 327 | 99 529 406 | NA | |
miR-106b | 99 529 552 | 99 529 633 | NA | |
miR-129-1 | 127 635 161 | 127 635 232 | NA | |
miR-182 | 129 197 459 | 129 197 568 | .0002 | |
miR-183 | 129 201 981 | 129 202 090 | .0035 | |
miR-29a | 130 212 046 | 130 212 109 | NA | |
miR-26b-1 | 130 212 758 | 130 212 838 | NA | |
Chr 8 (amplification) | miR-320a | 22 158 420 | 22 158 501 | NA |
miR-486 | 41 637 116 | 41 637 183 | NA | |
miR-30d | 135 886 301 | 135 886 370 | NA | |
miR-151 | 141 811 845 | 141 811 934 | .057 | |
Chr 9 | miR-101-2 | 4 840 297 | 4 840 375 | .54 |
miR-199b | 130 046 821 | 130 046 930 | NA | |
Chr 10 (deletion) | miR-146b | 104 186 259 | 104 186 331 | .0001 |
miR-1307 | 105 144 000 | 105 144 148 | NA | |
Chr 11 (amplification) | miR-130a | 57 165 247 | 57 165 335 | .0001 |
miR-192 | 64 415 185 | 64 415 294 | 0.68 | |
miR-34c | 110 889 374 | 110 889 450 | .0001 | |
let-7a-2 | 121 522 440 | 121 522 511 | .0001 | |
Chr 12 (deletion) | miR-200c | 6 943 123 | 6 943 190 | .027 |
miR-26a-2 | 56 504 659 | 56 504 742 | .0025 | |
let-7i | 61 283 733 | 61 283 816 | .045 | |
Chr 14 (amplification) | miR-342 | 99 645 745 | 99 645 843 | .0024 |
miR-493 | 100 405 150 | 100 405 238 | NA | |
miR-433 | 100 417 976 | 100 418 068 | NA | |
miR-127 | 100 419 069 | 100 419 165 | .0001 | |
miR-543 | 100 568 077 | 100 568 154 | NA | |
miR-495 | 100 569 845 | 100 569 926 | NA | |
miR-487b | 100 582 545 | 100 582 628 | NA | |
miR-889 | 100 583 991 | 100 584 069 | NA | |
Chr 15 (amplification) | miR-184 | 77 289 185 | 77 289 268 | .76 |
miR-9–3 | 87 712 252 | 87 712 341 | NA | |
Chr 17 (deletion) | miR-132 | 1 899 952 | 1 900 052 | .67 |
miR-744 | 11 925 941 | 11 926 038 | NA | |
Chr 18 (amplification) | miR-122 | 54 269 286 | 54 269 370 | .21 |
Chr 19 (amplification) | miR-199a-1 | 10 789 102 | 10 789 172 | NA |
miR-24–2 | 13 808 101 | 13 808 173 | NA | |
miR-27a | 13 808 254 | 13 808 331 | NA | |
miR-23a | 13 808 401 | 13 808 473 | NA | |
miR-1270 | 20 371 080 | 20 371 162 | NA | |
miR-330 | 50 834 092 | 50 834 185 | .013 | |
miR-99b | 56 887 677 | 56 887 746 | NA | |
let-7e | 56 887 851 | 56 887 929 | .52 | |
miR-125a | 56 888 319 | 56 888 404 | .0001 | |
miR-512-1 | 58 861 745 | 58 861 828 | NA | |
miR-512-2 | 58 864 223 | 58 864 320 | NA | |
miR-1323 | 58 867 034 | 58 867 106 | NA | |
miR-520a | 58 885 947 | 58 886 031 | NA | |
miR-518b | 58 897 803 | 58 897 885 | NA | |
miR-517a | 58 907 334 | 58 907 420 | NA | |
miR-517b | 58 916 142 | 58 916 208 | NA | |
miR-516b-2 | 58 920 508 | 58 920 592 | NA | |
miR-518a-1 | 58 926 072 | 58 926 156 | NA | |
miR-518a-2 | 58 934 399 | 58 934 485 | NA | |
miR-371 | 58 982 741 | 58 982 807 | .0001 | |
Chr 20 (amplification) | miR-103-2 | 3 846 141 | 3 846 218 | .086 |
miR-103-2-as | 3 846 149 | 3 846 210 | NA | |
Chr 21 (amplification) | let-7c | 16 834 019 | 16 834 102 | .0015 |
miR-125b-2 | 16 884 428 | 16 884 516 | .0001 | |
miR-155 | 25 868 163 | 25 868 227 | .0001 | |
Chr 22 (amplification) | miR-185 | 18 400 662 | 18 400 743 | .58 |
miR-130b | 20 337 593 | 20 337 674 | .0001 | |
chr X (deletion) | miR-221 | 45 490 529 | 45 490 638 | .02 |
miR-222 | 45 491 365 | 45 491 474 | .0001 | |
miR-98 | 53 599 909 | 53 600 027 | NA | |
let-7f-2 | 53 600 878 | 53 600 960 | NA | |
miR-1298 | 113 855 906 | 113 856 017 | NA | |
miR-363 | 133 131 074 | 133 131 148 | NA | |
miR-91a-2 | 133 131 234 | 133 131 308 | NA | |
miR-19b-2 | 133 131 367 | 133 131 462 | NA | |
miR-20b | 133 131 505 | 133 131 573 | NA |
Chromosome . | miR . | Bp start . | Bp end . | P* . |
---|---|---|---|---|
Chr 1 (amplification) | miR-30e | 40 s683 565 | 40 683 656 | .08 |
miR-30c-1 | 40 686 494 | 40 686 582 | NA | |
miR-101-1 | 65 296 705 | 65 296 779 | .0008 | |
miR-186 | 71 305 902 | 71 305 987 | .32 | |
miR-9-1 | 154 656 757 | 154 656 845 | .26 | |
miR-181b-1 | 197 094 625 | 197 094 734 | .0001 | |
miR-181a-1 | 197 094 796 | 197 094 905 | .0084 | |
miR-29c | 206 041 820 | 206 041 907 | NA | |
Chr 3 (deletion) | miR-128-2 | 35 760 972 | 35 761 055 | .0001 |
miR-26a-1 | 37 985 899 | 37 985 975 | .0001 | |
miR-138-1 | 44 130 708 | 44 130 806 | .11 | |
miR-425 | 49 032 585 | 49 032 671 | NA | |
miR-191 | 49 033 055 | 49 033 146 | .95 | |
let-7g | 52 277 334 | 52 277 417 | .0001 | |
miR-15b | 161 605 070 | 161 605 167 | NA | |
miR-16-2 | 161 605 227 | 161 605 307 | .042 | |
miR-28 | 189 889 263 | 189 889 348 | NA | |
Chr 5 (deletion) | miR-9-2 | 87 998 427 | 87 998 513 | NA |
miR-886 | 135 444 076 | 135 444 196 | NA | |
miR-143 | 148 788 674 | 148 788 779 | NA | |
miR-378 | 149 092 581 | 149 092 646 | NA | |
miR-146a | 159 844 937 | 159 845 035 | .0008 | |
miR-103-1 | 167 920 487 | 167 920 548 | NA | |
miR-340 | 179 374 909 | 179 375 003 | .0001 | |
Chr 6 (amplification) | miR-30a | 72 169 975 | 72 170 045 | NA |
Chr 7 (deletion) | miR-148a | 25 956 064 | 25 956 131 | .0001 |
miR-25 | 99 529 119 | 99 529 202 | NA | |
miR-93 | 99 529 327 | 99 529 406 | NA | |
miR-106b | 99 529 552 | 99 529 633 | NA | |
miR-129-1 | 127 635 161 | 127 635 232 | NA | |
miR-182 | 129 197 459 | 129 197 568 | .0002 | |
miR-183 | 129 201 981 | 129 202 090 | .0035 | |
miR-29a | 130 212 046 | 130 212 109 | NA | |
miR-26b-1 | 130 212 758 | 130 212 838 | NA | |
Chr 8 (amplification) | miR-320a | 22 158 420 | 22 158 501 | NA |
miR-486 | 41 637 116 | 41 637 183 | NA | |
miR-30d | 135 886 301 | 135 886 370 | NA | |
miR-151 | 141 811 845 | 141 811 934 | .057 | |
Chr 9 | miR-101-2 | 4 840 297 | 4 840 375 | .54 |
miR-199b | 130 046 821 | 130 046 930 | NA | |
Chr 10 (deletion) | miR-146b | 104 186 259 | 104 186 331 | .0001 |
miR-1307 | 105 144 000 | 105 144 148 | NA | |
Chr 11 (amplification) | miR-130a | 57 165 247 | 57 165 335 | .0001 |
miR-192 | 64 415 185 | 64 415 294 | 0.68 | |
miR-34c | 110 889 374 | 110 889 450 | .0001 | |
let-7a-2 | 121 522 440 | 121 522 511 | .0001 | |
Chr 12 (deletion) | miR-200c | 6 943 123 | 6 943 190 | .027 |
miR-26a-2 | 56 504 659 | 56 504 742 | .0025 | |
let-7i | 61 283 733 | 61 283 816 | .045 | |
Chr 14 (amplification) | miR-342 | 99 645 745 | 99 645 843 | .0024 |
miR-493 | 100 405 150 | 100 405 238 | NA | |
miR-433 | 100 417 976 | 100 418 068 | NA | |
miR-127 | 100 419 069 | 100 419 165 | .0001 | |
miR-543 | 100 568 077 | 100 568 154 | NA | |
miR-495 | 100 569 845 | 100 569 926 | NA | |
miR-487b | 100 582 545 | 100 582 628 | NA | |
miR-889 | 100 583 991 | 100 584 069 | NA | |
Chr 15 (amplification) | miR-184 | 77 289 185 | 77 289 268 | .76 |
miR-9–3 | 87 712 252 | 87 712 341 | NA | |
Chr 17 (deletion) | miR-132 | 1 899 952 | 1 900 052 | .67 |
miR-744 | 11 925 941 | 11 926 038 | NA | |
Chr 18 (amplification) | miR-122 | 54 269 286 | 54 269 370 | .21 |
Chr 19 (amplification) | miR-199a-1 | 10 789 102 | 10 789 172 | NA |
miR-24–2 | 13 808 101 | 13 808 173 | NA | |
miR-27a | 13 808 254 | 13 808 331 | NA | |
miR-23a | 13 808 401 | 13 808 473 | NA | |
miR-1270 | 20 371 080 | 20 371 162 | NA | |
miR-330 | 50 834 092 | 50 834 185 | .013 | |
miR-99b | 56 887 677 | 56 887 746 | NA | |
let-7e | 56 887 851 | 56 887 929 | .52 | |
miR-125a | 56 888 319 | 56 888 404 | .0001 | |
miR-512-1 | 58 861 745 | 58 861 828 | NA | |
miR-512-2 | 58 864 223 | 58 864 320 | NA | |
miR-1323 | 58 867 034 | 58 867 106 | NA | |
miR-520a | 58 885 947 | 58 886 031 | NA | |
miR-518b | 58 897 803 | 58 897 885 | NA | |
miR-517a | 58 907 334 | 58 907 420 | NA | |
miR-517b | 58 916 142 | 58 916 208 | NA | |
miR-516b-2 | 58 920 508 | 58 920 592 | NA | |
miR-518a-1 | 58 926 072 | 58 926 156 | NA | |
miR-518a-2 | 58 934 399 | 58 934 485 | NA | |
miR-371 | 58 982 741 | 58 982 807 | .0001 | |
Chr 20 (amplification) | miR-103-2 | 3 846 141 | 3 846 218 | .086 |
miR-103-2-as | 3 846 149 | 3 846 210 | NA | |
Chr 21 (amplification) | let-7c | 16 834 019 | 16 834 102 | .0015 |
miR-125b-2 | 16 884 428 | 16 884 516 | .0001 | |
miR-155 | 25 868 163 | 25 868 227 | .0001 | |
Chr 22 (amplification) | miR-185 | 18 400 662 | 18 400 743 | .58 |
miR-130b | 20 337 593 | 20 337 674 | .0001 | |
chr X (deletion) | miR-221 | 45 490 529 | 45 490 638 | .02 |
miR-222 | 45 491 365 | 45 491 474 | .0001 | |
miR-98 | 53 599 909 | 53 600 027 | NA | |
let-7f-2 | 53 600 878 | 53 600 960 | NA | |
miR-1298 | 113 855 906 | 113 856 017 | NA | |
miR-363 | 133 131 074 | 133 131 148 | NA | |
miR-91a-2 | 133 131 234 | 133 131 308 | NA | |
miR-19b-2 | 133 131 367 | 133 131 462 | NA | |
miR-20b | 133 131 505 | 133 131 573 | NA |
Bp indicates base pair; as, antisense; and NA, not available.
Value was generated from microarray data when comparing miRNA expression changes between AML patient (n = 58) and control CD34+ samples (n =11).