Table 3

Administered therapy

Treatment
Total no. of cycles 373 
Cycles per patient, no. of cycles  
    Median 
    Range 1-57 
Cycles per patient, no. of patients  
    ≤ 2 22 
    3-5 
    ≥ 6 16 
No. of doses per patient  
    Median 
    Range 1-169 
No. of doses  
    Total 1062 
    Full 510 
    Dose escalated 135 
    Reduced, total* 417 
        Reduced due to toxicity 137 
    Held 
Dose administered  
    Cumulative dose, mg/m2  
        Median 112 
        Range 14-1176 
    Cumulative dose, mg  
        Median 196 
        Range 25-2391 
Treatment
Total no. of cycles 373 
Cycles per patient, no. of cycles  
    Median 
    Range 1-57 
Cycles per patient, no. of patients  
    ≤ 2 22 
    3-5 
    ≥ 6 16 
No. of doses per patient  
    Median 
    Range 1-169 
No. of doses  
    Total 1062 
    Full 510 
    Dose escalated 135 
    Reduced, total* 417 
        Reduced due to toxicity 137 
    Held 
Dose administered  
    Cumulative dose, mg/m2  
        Median 112 
        Range 14-1176 
    Cumulative dose, mg  
        Median 196 
        Range 25-2391 
*

Total number of dosese reduced includes those on a stable dose reduction, required to prevent recurrence of toxicity.

According to protocol criteria.

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