Table 1 PEST mutations occur at high... | American Society of Hematology

Table 1

PEST mutations occur at high frequency in ERG-expressing T-cell tumors

Tumor	PEST mutation*	Mutational consequence†
e	Deletion AGCAGTCTGCCTGTGCA 7534	Frameshift, Δ2484
f	Insertion GG/deletion C 7316	Frameshift, Δ2490
g	Insertion CC/deletion G 7346	Frameshift, Δ2490
h	Insertion C 7666	Frameshift, Δ2506
i	Deletion ATGTACAACCGCTGGG 7514	Frameshift, Δ2446

Tumor	PEST mutation*	Mutational consequence†
e	Deletion AGCAGTCTGCCTGTGCA 7534	Frameshift, Δ2484
f	Insertion GG/deletion C 7316	Frameshift, Δ2490
g	Insertion CC/deletion G 7346	Frameshift, Δ2490
h	Insertion C 7666	Frameshift, Δ2506
i	Deletion ATGTACAACCGCTGGG 7514	Frameshift, Δ2446

Tumors e to f correspond to those indicated in Figure 1G. No HD mutations were observed.

Numbers correspond to nucleotide positions in Notch1 cDNA.

Numbers indicate amino acid residues in Notch1 at which mutations occur.