QITP antibodies binding to human platelets, CHO cells expressing human GPIb/IX or GPIIb/IIIa, and mature human megakaryocytes in vitro
| Patient . | Platelets . | CHO-Ib/IX . | CHO-IIb/IIIa . | Mature Mks . | ||||
|---|---|---|---|---|---|---|---|---|
| −Qn . | +Qn . | −Qn . | +Qn . | −Qn . | +Qn . | −Qn . | +Qn . | |
| FC | 11.2 | 70.8 | 2.8 | 51.1 | 3.0 | 2.5 | 4.05 | 38.3 |
| JM | 1.3 | 85.9 | 0.9 | 53.7 | 1.7 | 0.9 | ND | ND |
| WJ | 3.6 | 87.9 | 0.9 | 85.5 | 1.0 | 10.4 | 6.18 | 66.7 |
| JG | 1.6 | 95.6 | 2.4 | 62.2 | 43.2 | 47.9 | 15.4 | 70.0 |
| JE | 9.2 | 94.2 | 1.5 | 54.7 | 2.3 | 14.7 | 8.9 | 86.6 |
| NS | 1.3 | 1.4 | ND | 1.6 | ND | 3.0 | ND | 5.3 |
| Patient . | Platelets . | CHO-Ib/IX . | CHO-IIb/IIIa . | Mature Mks . | ||||
|---|---|---|---|---|---|---|---|---|
| −Qn . | +Qn . | −Qn . | +Qn . | −Qn . | +Qn . | −Qn . | +Qn . | |
| FC | 11.2 | 70.8 | 2.8 | 51.1 | 3.0 | 2.5 | 4.05 | 38.3 |
| JM | 1.3 | 85.9 | 0.9 | 53.7 | 1.7 | 0.9 | ND | ND |
| WJ | 3.6 | 87.9 | 0.9 | 85.5 | 1.0 | 10.4 | 6.18 | 66.7 |
| JG | 1.6 | 95.6 | 2.4 | 62.2 | 43.2 | 47.9 | 15.4 | 70.0 |
| JE | 9.2 | 94.2 | 1.5 | 54.7 | 2.3 | 14.7 | 8.9 | 86.6 |
| NS | 1.3 | 1.4 | ND | 1.6 | ND | 3.0 | ND | 5.3 |
Percentage of positive cells as determined by flow cytometry.
ND indicates not determined.