Standardized incidence ratios and absolute excess risks of cardiovascular disease after NHL treatment
Event . | No. Observed* . | No. Expected . | SIR (95% CI) . | AER per 10 000 person-years . | Median age at event, y (range) . | Median interval of treatment until event, y (range) . |
|---|---|---|---|---|---|---|
| Chronic heart failure | 64 | 12.0 | 5.4 (4.1-6.9) | 208 | 53.6 (38-82) | 3.4 (2.3-4.6) |
| Coronary artery disease | 20 | 30.4 | 0.7 (0.4-0.9) | –38 | 53.1 (34-89) | 2.5 (1.8-3.4) |
| Myocardial infarction | 17 | 14.8 | 1.2 (0.8-2.4) | 8 | 49.3 (38-73) | 2.6 (2.0-3.4) |
| Angina pectoris | 16 | 19.6 | 0.8 (0.4-1.3) | –14 | 54.1 (34-89) | 2.4 (1.8-3.2) |
| Stroke | 11 | 7.3 | 1.5 (1.1-2.7) | 15 | 62.1 (39-79) | 3.7 (1.6-5.1) |
Event . | No. Observed* . | No. Expected . | SIR (95% CI) . | AER per 10 000 person-years . | Median age at event, y (range) . | Median interval of treatment until event, y (range) . |
|---|---|---|---|---|---|---|
| Chronic heart failure | 64 | 12.0 | 5.4 (4.1-6.9) | 208 | 53.6 (38-82) | 3.4 (2.3-4.6) |
| Coronary artery disease | 20 | 30.4 | 0.7 (0.4-0.9) | –38 | 53.1 (34-89) | 2.5 (1.8-3.4) |
| Myocardial infarction | 17 | 14.8 | 1.2 (0.8-2.4) | 8 | 49.3 (38-73) | 2.6 (2.0-3.4) |
| Angina pectoris | 16 | 19.6 | 0.8 (0.4-1.3) | –14 | 54.1 (34-89) | 2.4 (1.8-3.2) |
| Stroke | 11 | 7.3 | 1.5 (1.1-2.7) | 15 | 62.1 (39-79) | 3.7 (1.6-5.1) |
Observed in 476 patients for myocardial infarction (1980-2000) and in 441 patients for chronic heart failure and stroke (1985-2000)