Table 1 Summary of neonates collected... | American Society of Hematology

Table 1

Summary of neonates collected from heterozygous (fII^WT/WE) breeding pairs

	fII^WT/WT (wild-type)	fII^WT/WE (hemizygous)	fII^WE/WE (homozygous)
Number observed*	46	78^†	17^‡
Percentage expected	25%	50%	25%
Percentage observed	32.6%	55%	12%
Number (percentage) of expected based on wild-type	46 (100%)	92 (85%)	46 (37%)

	fII^WT/WT (wild-type)	fII^WT/WE (hemizygous)	fII^WE/WE (homozygous)
Number observed*	46	78^†	17^‡
Percentage expected	25%	50%	25%
Percentage observed	32.6%	55%	12%
Number (percentage) of expected based on wild-type	46 (100%)	92 (85%)	46 (37%)

P < 0.002 by χ² analysis.

Four died within 1 day of birth: 3 with abdominal hemorrhage and 1 with head and neck bleed.

All 17 nulls died prior to weaning: 1 mouse lived 14 days, 1 died after 2 days, and the others died after 1 day or at birth.