Pseudo-first-order rate constants (k) for the APC-catalyzed inactivation of FVa R506Q/R679Q in the presence and absence of WT protein S and protein S E36A
| . | No protein S . | WT protein S . | Protein S E36A . |
|---|---|---|---|
| k (M−1̇ s−1) | 1.63 ± 0.92 × 106 | 3.77 ± 1.66 × 107 | 4.15 ± 3.18 × 106 |
| Fold enhancement | 1 | 24.7 ± 5.34 | 2.75 ± 1.76 |
| . | No protein S . | WT protein S . | Protein S E36A . |
|---|---|---|---|
| k (M−1̇ s−1) | 1.63 ± 0.92 × 106 | 3.77 ± 1.66 × 107 | 4.15 ± 3.18 × 106 |
| Fold enhancement | 1 | 24.7 ± 5.34 | 2.75 ± 1.76 |
Rate constants are given as mean ± SD from 4 independent experiments.