Table 2

Late bacterial infection (> day 100, 121 infections occurring in 54 patients: 25 ATG-F, 29 control)

SpeciesNLocation: bloodstream/pneumonia/urinary/otherMedian elapsed time (range)ATG-F/control
Streptococcal 29 6/2/10/11 315 (120-1479) 17/12 
Staphylococcal 22 13/5/0/4 223 (105-1164) 9/13 
Klebsiella 11 3/1/4/3 227 (103-431) 8/3 
Pseudomonas 16 9/0/0/7 190 (118-418) 2/14 
Other specified 20 6/4/3/7 292 (107-1390) 9/11 
Other nonspecified 23 10/6/2/5 176 (101-1385) 12/11 
All 121 47/18/19/37 245 (101-1479) 57/64 
SpeciesNLocation: bloodstream/pneumonia/urinary/otherMedian elapsed time (range)ATG-F/control
Streptococcal 29 6/2/10/11 315 (120-1479) 17/12 
Staphylococcal 22 13/5/0/4 223 (105-1164) 9/13 
Klebsiella 11 3/1/4/3 227 (103-431) 8/3 
Pseudomonas 16 9/0/0/7 190 (118-418) 2/14 
Other specified 20 6/4/3/7 292 (107-1390) 9/11 
Other nonspecified 23 10/6/2/5 176 (101-1385) 12/11 
All 121 47/18/19/37 245 (101-1479) 57/64 

Infectious-related deaths after day 100: ATG-F arm: 5 deaths: streptococcal sepsis (1), sepsis, not otherwise specified (2), CMV disease (1), and influenzae pneumonia (1). Of those 5 deaths, the 2 sepsis occurred in context of cGVHD. Control arm: 4 deaths: toxoplasma (1), Pseudomonas species (1), aspergillosis (1), and legionella (1). All 4 of those deaths occurred in context of cGVHD.

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