Table 1 Summary of GRADE recommendations... | American Society of Hematology

Table 1

Summary of GRADE recommendations for grading levels of evidence

Grade
1	Evidence strongly suggests that the benefit of the procedure outweighs potential risk or risks of the procedure outweighs potential benefits	A	Consistent evidence from systematic reviews or high quality randomized studies or high quality observational studies
		B	Evidence from randomized and observational studies with important methodological flaws
2	Evidence suggests the benefit and risk of a procedure is finely balanced or uncertain	C	Evidence from randomized and observational studies with major methodological flaws or other sources of evidence e.g. case series

Grade
1	Evidence strongly suggests that the benefit of the procedure outweighs potential risk or risks of the procedure outweighs potential benefits	A	Consistent evidence from systematic reviews or high quality randomized studies or high quality observational studies
		B	Evidence from randomized and observational studies with important methodological flaws
2	Evidence suggests the benefit and risk of a procedure is finely balanced or uncertain	C	Evidence from randomized and observational studies with major methodological flaws or other sources of evidence e.g. case series

Each recommendation in the guideline is given a numerical score which denotes how likely the patient is to gain benefit from the intervention and a letter which demonstrates the strength of the evidence.³

View Large

This Feature Is Available To Subscribers Only