Association of F220210G>A genotype with CRP levels
| CRP . | Carriage of F220210A versus F220210GG . | |||||
|---|---|---|---|---|---|---|
| Univariate . | Multivariate . | |||||
| OR . | 95% CI (P) . | 95% CI (P)* . | OR . | 95% CI (P) . | 95% CI (P)* . | |
| ≥ 5 mg/L | 2.04 | 1.44-2.89 (< .0001) | 1.12-3.72 (< .02) | 1.91 | 1.32-2.75 (< .0005) | 1.00-3.67 (.05) |
| ≥ 10 mg/L | 2.99 | 1.98-4.48 (< 10−6) | 1.49-5.98 (.002) | 3.21 | 2.11-4.88 (< 10−7) | 1.61-6.37 (< .001) |
| ≥ 15 mg/L | 2.64 | 1.51-4.62 (< .001) | 1.18-5.93 (< .02) | 2.86 | 1.62-5.06 (< .0005) | 1.29-6.34 (< .01) |
| CRP . | Carriage of F220210A versus F220210GG . | |||||
|---|---|---|---|---|---|---|
| Univariate . | Multivariate . | |||||
| OR . | 95% CI (P) . | 95% CI (P)* . | OR . | 95% CI (P) . | 95% CI (P)* . | |
| ≥ 5 mg/L | 2.04 | 1.44-2.89 (< .0001) | 1.12-3.72 (< .02) | 1.91 | 1.32-2.75 (< .0005) | 1.00-3.67 (.05) |
| ≥ 10 mg/L | 2.99 | 1.98-4.48 (< 10−6) | 1.49-5.98 (.002) | 3.21 | 2.11-4.88 (< 10−7) | 1.61-6.37 (< .001) |
| ≥ 15 mg/L | 2.64 | 1.51-4.62 (< .001) | 1.18-5.93 (< .02) | 2.86 | 1.62-5.06 (< .0005) | 1.29-6.34 (< .01) |
Analyses based on 565 patients and 2258 observations. Multivariate analyses were adjusted for weeks of gestation, age and ethnicity.
F220210A indicates carriage of prothrombin 20210A variant; F220210GG, prothrombin 20210GG wild-type; OR, odds ratio; and CI, confidence interval.
95% CI and P value after adjustment for nonindependent observations within clusters.