Table 1

Subject characteristics (n = 15)

CharacteristicValue
Median age, y (range) 45 (20-68) 
Patient sex, male/female, n 10/5 
Donor type, n  
    Matched related donor 
    Matched unrelated donor 
Graft source, n  
    Peripheral blood 13 
    Bone marrow 
Diagnosis, n  
    Acute lymphoblastic leukemia 
    Acute myeloid leukemia 
    Chronic myeloid leukemia 
    Chronic lymphocytic leukemia 
    Mantle cell lymphoma 
    Multiple myeloma 
    Non-Hodgkin lymphoma 
    Polycythemia vera/myelofibrosis 
    Sezary syndrome 
    Systemic lupus erythematosus 
Median days status after transplantation at enrollment (range) 1270 (100-4334) 
Median no. of secondary therapies before study enrollment (range) 3 (2-5) 
cGVHD primary therapy, n  
    Prednisone 13 
    Prednisone/cyclosporine 
cGVHD secondary therapies, n  
    Cyclosporine 
    Extracorporeal photopheresis 
    Tacrolimus 
    Mycophenolate mofetil 
    Pentostatin 
    Plaquenil 
    Rituximab 
    Daclizumab 
cGVHD organ involvement upon study enrollment, n  
    Skin/connective tissue 13 
    Oropharynx 12 
    Liver (total bilirubin) 
    Liver (AST, ALT, alkaline phosphatase) 
    Esophagus/lower GI 
    Ocular 
    Lung 
CharacteristicValue
Median age, y (range) 45 (20-68) 
Patient sex, male/female, n 10/5 
Donor type, n  
    Matched related donor 
    Matched unrelated donor 
Graft source, n  
    Peripheral blood 13 
    Bone marrow 
Diagnosis, n  
    Acute lymphoblastic leukemia 
    Acute myeloid leukemia 
    Chronic myeloid leukemia 
    Chronic lymphocytic leukemia 
    Mantle cell lymphoma 
    Multiple myeloma 
    Non-Hodgkin lymphoma 
    Polycythemia vera/myelofibrosis 
    Sezary syndrome 
    Systemic lupus erythematosus 
Median days status after transplantation at enrollment (range) 1270 (100-4334) 
Median no. of secondary therapies before study enrollment (range) 3 (2-5) 
cGVHD primary therapy, n  
    Prednisone 13 
    Prednisone/cyclosporine 
cGVHD secondary therapies, n  
    Cyclosporine 
    Extracorporeal photopheresis 
    Tacrolimus 
    Mycophenolate mofetil 
    Pentostatin 
    Plaquenil 
    Rituximab 
    Daclizumab 
cGVHD organ involvement upon study enrollment, n  
    Skin/connective tissue 13 
    Oropharynx 12 
    Liver (total bilirubin) 
    Liver (AST, ALT, alkaline phosphatase) 
    Esophagus/lower GI 
    Ocular 
    Lung 

AST indicates aspartate aminotransferase; and ALT, alanine aminotransferase.

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