Table 1

B and T leukemia immunophenotype

Probe setGeneSamples
T1-CT*T2-CT*T3-CT*B1-CT*B2-CT*B3-CT*CT†T1†T2†T3†CB†B1†B2†B3†M†CE†E1†E2†E3†Mk1†Mk2†Mk3†
B-cell phenotype 
1418065_at Rag2 −5.33 −3.59 −6.40 1.40 4.23 4.83 4.81 −0.52 1.22 −1.59 −1.09 0.32 3.14 3.74 −1.19 −1.01 −1.46 −1.48 −1.21 −1.16 −1.40 −1.10 
1449869_at Vpreb1 −1.61 −1.73 −1.54 7.48 7.42 7.42 −0.71 −2.32 −2.44 −2.25 −0.77 6.72 6.66 6.65 −1.86 −1.11 1.38 −2.11 −2.22 −1.33 −2.22 −2.08 
1420176_x_at Igll1 −0.27 0.14 −0.04 7.08 7.05 7.00 −1.89 −2.17 −1.75 −1.93 −0.74 6.34 6.31 6.26 −0.68 −1.12 0.59 −1.92 −1.64 −1.81 −1.94 −1.92 
1448649_at Enpep −0.02 −0.24 −0.17 9.58 9.56 9.18 −1.80 −1.81 −2.04 −1.97 −1.99 7.59 7.57 7.18 −2.01 −1.51 0.52 −1.78 −1.83 −2.01 −2.10 −2.01 
1439820_at Ebf1 −0.08 −0.09 −0.13 4.48 4.48 3.95 −1.00 −1.08 −1.09 −1.13 −0.56 3.93 3.93 3.39 −1.14 −0.88 −0.86 −1.31 −0.96 −0.91 −0.79 0.46 
1448575_at Il7r 3.40 2.48 0.56 7.82 7.71 7.05 0.21 3.62 2.70 0.77 −2.80 5.02 4.91 4.25 −1.87 −1.15 −1.59 −3.54 −3.22 −2.99 −3.24 −1.09 
1449454_at Bst1 0.24 1.63 0.29 6.37 6.94 6.21 −1.65 −1.40 −0.01 −1.36 −1.40 4.97 5.54 4.81 −1.33 0.21 −1.46 −1.55 −1.57 −1.24 −1.24 −1.31 
1438802_at Foxp1 0.01 0.40 −1.83 2.39 2.78 2.22 0.44 0.45 0.84 −1.39 −0.56 1.84 2.22 1.66 0.00 −1.67 −1.31 −1.93 −1.54 −0.15 0.53 0.59 
1418830_at Cd79a −0.10 0.05 0.64 −0.11 −0.39 −0.11 −3.09 −3.19 −3.04 −2.45 5.37 5.25 4.98 5.26 −2.23 −1.49 −1.20 −2.85 −3.24 −2.57 2.02 2.49 
1417640_at Cd79b −3.05 −3.35 −2.52 −0.80 −0.71 −0.83 −0.59 −3.64 −3.94 −3.11 4.84 4.04 4.13 4.02 −0.17 −0.93 −1.22 −3.34 −3.86 −0.52 2.03 2.27 
1421475_at Ms4a2 −0.13 0.04 −0.04 0.04 0.19 0.14 −0.15 −0.28 −0.12 −0.19 −0.39 −0.35 −0.19 −0.25 −0.38 0.00 −0.33 −0.36 −0.13 −0.10 0.83 2.40 
1422124_a_at Ptprc (CD45R) −0.01 0.32 −0.29 −0.01 −0.55 −0.77 1.58 1.57 1.90 1.29 1.29 1.28 0.74 0.52 0.77 −0.46 −2.89 −4.24 −5.76 0.45 0.98 1.00 
1440165_at Ptprc (CD45R) 0.23 1.97 −1.04 0.94 0.15 −0.58 1.46 1.70 3.44 0.42 0.51 1.46 0.67 −0.07 1.92 −1.95 −2.47 −3.27 −2.76 −1.42 0.10 0.26 
1450570_a_at Cd19 −0.29 −0.68 0.37 0.37 0.14 0.20 −2.48 −2.77 −3.16 −2.11 4.68 5.05 4.82 4.88 −2.24 −1.36 −1.20 −2.56 −2.48 −2.14 0.98 2.09 
1417185_at Ly6a (Sca-1) −1.71 −4.16 −2.23 −4.40 −3.88 0.66 0.84 −0.87 −3.32 −1.39 3.76 −0.65 −0.12 4.42 −0.30 −0.07 −0.34 −1.82 −2.75 −0.58 1.15 2.05 
T-cell phenotype 
1419696_at Cd4 −3.45 −5.98 −1.62 −0.46 −0.46 −0.49 4.99 1.54 −0.98 3.37 −0.52 −0.98 −0.98 −1.01 −0.87 0.24 −0.69 −0.72 −0.95 −0.88 −0.93 −0.63 
1427779_a_at Cd4 −3.66 −4.92 −1.35 −0.72 −0.77 −0.82 4.38 0.72 −0.53 3.03 −0.04 −0.75 −0.80 −0.86 −0.75 −0.18 −0.62 −0.80 −0.57 −0.86 −0.83 −0.57 
1425335_at Cd8a −4.34 −1.84 −8.29 −0.73 −0.80 −0.97 7.04 2.70 5.20 −1.25 −0.44 −1.17 −1.23 −1.41 −1.16 −1.15 −1.01 −1.24 −1.35 −0.98 −1.37 −1.18 
1444078_at Cd8a −3.16 −0.98 −7.74 −0.55 −0.58 −0.11 6.43 3.28 5.45 −1.30 −0.88 −1.43 −1.47 −0.99 −0.97 −0.68 −1.26 −1.39 −1.13 −1.02 −1.33 −1.31 
1451673_at Cd8a −3.49 −1.53 −8.99 0.11 0.01 −0.41 7.49 4.00 5.96 −1.49 −1.13 −1.02 −1.12 −1.54 −1.43 −1.41 −1.41 −1.57 −1.58 −1.05 −1.50 −1.21 
1422105_at Cd3e −0.69 −0.47 −0.22 −0.12 −0.30 −0.07 3.76 3.07 3.29 3.54 −1.07 −1.19 −1.37 −1.14 −1.13 −0.79 −1.22 −1.21 −1.43 −0.64 −1.38 −1.10 
1422828_at Cd3d −0.29 −0.29 −0.43 −2.31 −2.09 −2.21 5.68 5.39 5.39 5.25 −0.60 −2.91 −2.69 −2.81 −0.65 0.43 −2.11 −2.47 −2.57 −1.29 −2.55 −1.50 
1451910_a_at Cd6 −1.27 −1.87 −0.68 0.29 0.19 0.03 4.81 3.53 2.94 4.13 −1.15 −0.86 −0.96 −1.12 −1.39 −1.34 −1.65 −1.55 −1.12 −0.98 −1.77 −1.53 
1418770_at Cd2 −0.27 0.50 −0.95 −3.53 −2.71 −1.84 3.27 3.00 3.78 2.33 3.66 0.13 0.95 1.82 −3.08 −3.19 −3.21 −3.23 −3.25 −2.19 −0.73 −0.06 
1418353_at Cd5 −0.86 −1.95 0.10 2.49 −0.48 2.25 4.48 3.62 2.53 4.58 −0.13 2.36 −0.61 2.13 −2.06 −2.61 −2.46 −2.75 −2.45 −2.47 −2.30 −1.87 
1420066_s_at Cd160 2.40 2.54 3.75 −0.04 −0.17 2.42 −0.68 1.72 1.86 3.06 −0.58 −0.62 −0.75 1.84 −0.64 −0.52 −0.88 −0.85 −0.99 −0.72 −0.70 −0.55 
1420396_at Cd160 2.04 2.16 3.39 −0.39 −0.39 2.52 −0.34 1.71 1.82 3.06 −0.55 −0.94 −0.93 1.97 −1.00 −0.59 −0.86 −0.73 −0.78 −0.28 −1.03 −0.53 
1415797_at Cd28 0.16 −0.71 0.30 0.27 −0.22 −0.27 5.19 5.35 4.48 5.49 −1.90 −1.63 −2.12 −2.17 −1.53 −2.14 −2.08 −2.03 −1.99 −1.99 0.63 −1.58 
1419226_at Cd96 −2.01 −0.16 −0.99 −0.32 0.11 0.11 2.89 0.88 2.73 1.90 −2.38 −2.70 −2.27 −2.27 −0.96 −0.40 0.24 −2.27 −2.74 1.86 3.37 2.12 
1441552_at Tcra 2.62 3.05 1.03 −0.11 −0.18 −0.05 0.60 3.22 3.65 1.63 −0.75 −0.86 −0.92 −0.80 −0.89 −0.64 −0.63 −0.90 −0.63 −0.53 −0.87 −0.71 
1449757_x_at Dntt (TdT) −1.68 −2.13 −8.56 0.14 −0.01 6.32 6.63 4.94 4.49 −1.94 −1.70 −1.56 −1.71 4.62 −2.05 −1.31 −1.88 −1.62 −1.75 −1.67 −1.83 −1.67 
1419711_at Cd7 −0.43 0.57 −3.54 −1.28 −1.35 −1.05 1.22 0.79 1.79 −2.32 −0.99 −2.26 −2.34 −2.03 −0.81 −1.11 3.77 2.26 0.75 0.78 −1.72 2.22 
Probe setGeneSamples
T1-CT*T2-CT*T3-CT*B1-CT*B2-CT*B3-CT*CT†T1†T2†T3†CB†B1†B2†B3†M†CE†E1†E2†E3†Mk1†Mk2†Mk3†
B-cell phenotype 
1418065_at Rag2 −5.33 −3.59 −6.40 1.40 4.23 4.83 4.81 −0.52 1.22 −1.59 −1.09 0.32 3.14 3.74 −1.19 −1.01 −1.46 −1.48 −1.21 −1.16 −1.40 −1.10 
1449869_at Vpreb1 −1.61 −1.73 −1.54 7.48 7.42 7.42 −0.71 −2.32 −2.44 −2.25 −0.77 6.72 6.66 6.65 −1.86 −1.11 1.38 −2.11 −2.22 −1.33 −2.22 −2.08 
1420176_x_at Igll1 −0.27 0.14 −0.04 7.08 7.05 7.00 −1.89 −2.17 −1.75 −1.93 −0.74 6.34 6.31 6.26 −0.68 −1.12 0.59 −1.92 −1.64 −1.81 −1.94 −1.92 
1448649_at Enpep −0.02 −0.24 −0.17 9.58 9.56 9.18 −1.80 −1.81 −2.04 −1.97 −1.99 7.59 7.57 7.18 −2.01 −1.51 0.52 −1.78 −1.83 −2.01 −2.10 −2.01 
1439820_at Ebf1 −0.08 −0.09 −0.13 4.48 4.48 3.95 −1.00 −1.08 −1.09 −1.13 −0.56 3.93 3.93 3.39 −1.14 −0.88 −0.86 −1.31 −0.96 −0.91 −0.79 0.46 
1448575_at Il7r 3.40 2.48 0.56 7.82 7.71 7.05 0.21 3.62 2.70 0.77 −2.80 5.02 4.91 4.25 −1.87 −1.15 −1.59 −3.54 −3.22 −2.99 −3.24 −1.09 
1449454_at Bst1 0.24 1.63 0.29 6.37 6.94 6.21 −1.65 −1.40 −0.01 −1.36 −1.40 4.97 5.54 4.81 −1.33 0.21 −1.46 −1.55 −1.57 −1.24 −1.24 −1.31 
1438802_at Foxp1 0.01 0.40 −1.83 2.39 2.78 2.22 0.44 0.45 0.84 −1.39 −0.56 1.84 2.22 1.66 0.00 −1.67 −1.31 −1.93 −1.54 −0.15 0.53 0.59 
1418830_at Cd79a −0.10 0.05 0.64 −0.11 −0.39 −0.11 −3.09 −3.19 −3.04 −2.45 5.37 5.25 4.98 5.26 −2.23 −1.49 −1.20 −2.85 −3.24 −2.57 2.02 2.49 
1417640_at Cd79b −3.05 −3.35 −2.52 −0.80 −0.71 −0.83 −0.59 −3.64 −3.94 −3.11 4.84 4.04 4.13 4.02 −0.17 −0.93 −1.22 −3.34 −3.86 −0.52 2.03 2.27 
1421475_at Ms4a2 −0.13 0.04 −0.04 0.04 0.19 0.14 −0.15 −0.28 −0.12 −0.19 −0.39 −0.35 −0.19 −0.25 −0.38 0.00 −0.33 −0.36 −0.13 −0.10 0.83 2.40 
1422124_a_at Ptprc (CD45R) −0.01 0.32 −0.29 −0.01 −0.55 −0.77 1.58 1.57 1.90 1.29 1.29 1.28 0.74 0.52 0.77 −0.46 −2.89 −4.24 −5.76 0.45 0.98 1.00 
1440165_at Ptprc (CD45R) 0.23 1.97 −1.04 0.94 0.15 −0.58 1.46 1.70 3.44 0.42 0.51 1.46 0.67 −0.07 1.92 −1.95 −2.47 −3.27 −2.76 −1.42 0.10 0.26 
1450570_a_at Cd19 −0.29 −0.68 0.37 0.37 0.14 0.20 −2.48 −2.77 −3.16 −2.11 4.68 5.05 4.82 4.88 −2.24 −1.36 −1.20 −2.56 −2.48 −2.14 0.98 2.09 
1417185_at Ly6a (Sca-1) −1.71 −4.16 −2.23 −4.40 −3.88 0.66 0.84 −0.87 −3.32 −1.39 3.76 −0.65 −0.12 4.42 −0.30 −0.07 −0.34 −1.82 −2.75 −0.58 1.15 2.05 
T-cell phenotype 
1419696_at Cd4 −3.45 −5.98 −1.62 −0.46 −0.46 −0.49 4.99 1.54 −0.98 3.37 −0.52 −0.98 −0.98 −1.01 −0.87 0.24 −0.69 −0.72 −0.95 −0.88 −0.93 −0.63 
1427779_a_at Cd4 −3.66 −4.92 −1.35 −0.72 −0.77 −0.82 4.38 0.72 −0.53 3.03 −0.04 −0.75 −0.80 −0.86 −0.75 −0.18 −0.62 −0.80 −0.57 −0.86 −0.83 −0.57 
1425335_at Cd8a −4.34 −1.84 −8.29 −0.73 −0.80 −0.97 7.04 2.70 5.20 −1.25 −0.44 −1.17 −1.23 −1.41 −1.16 −1.15 −1.01 −1.24 −1.35 −0.98 −1.37 −1.18 
1444078_at Cd8a −3.16 −0.98 −7.74 −0.55 −0.58 −0.11 6.43 3.28 5.45 −1.30 −0.88 −1.43 −1.47 −0.99 −0.97 −0.68 −1.26 −1.39 −1.13 −1.02 −1.33 −1.31 
1451673_at Cd8a −3.49 −1.53 −8.99 0.11 0.01 −0.41 7.49 4.00 5.96 −1.49 −1.13 −1.02 −1.12 −1.54 −1.43 −1.41 −1.41 −1.57 −1.58 −1.05 −1.50 −1.21 
1422105_at Cd3e −0.69 −0.47 −0.22 −0.12 −0.30 −0.07 3.76 3.07 3.29 3.54 −1.07 −1.19 −1.37 −1.14 −1.13 −0.79 −1.22 −1.21 −1.43 −0.64 −1.38 −1.10 
1422828_at Cd3d −0.29 −0.29 −0.43 −2.31 −2.09 −2.21 5.68 5.39 5.39 5.25 −0.60 −2.91 −2.69 −2.81 −0.65 0.43 −2.11 −2.47 −2.57 −1.29 −2.55 −1.50 
1451910_a_at Cd6 −1.27 −1.87 −0.68 0.29 0.19 0.03 4.81 3.53 2.94 4.13 −1.15 −0.86 −0.96 −1.12 −1.39 −1.34 −1.65 −1.55 −1.12 −0.98 −1.77 −1.53 
1418770_at Cd2 −0.27 0.50 −0.95 −3.53 −2.71 −1.84 3.27 3.00 3.78 2.33 3.66 0.13 0.95 1.82 −3.08 −3.19 −3.21 −3.23 −3.25 −2.19 −0.73 −0.06 
1418353_at Cd5 −0.86 −1.95 0.10 2.49 −0.48 2.25 4.48 3.62 2.53 4.58 −0.13 2.36 −0.61 2.13 −2.06 −2.61 −2.46 −2.75 −2.45 −2.47 −2.30 −1.87 
1420066_s_at Cd160 2.40 2.54 3.75 −0.04 −0.17 2.42 −0.68 1.72 1.86 3.06 −0.58 −0.62 −0.75 1.84 −0.64 −0.52 −0.88 −0.85 −0.99 −0.72 −0.70 −0.55 
1420396_at Cd160 2.04 2.16 3.39 −0.39 −0.39 2.52 −0.34 1.71 1.82 3.06 −0.55 −0.94 −0.93 1.97 −1.00 −0.59 −0.86 −0.73 −0.78 −0.28 −1.03 −0.53 
1415797_at Cd28 0.16 −0.71 0.30 0.27 −0.22 −0.27 5.19 5.35 4.48 5.49 −1.90 −1.63 −2.12 −2.17 −1.53 −2.14 −2.08 −2.03 −1.99 −1.99 0.63 −1.58 
1419226_at Cd96 −2.01 −0.16 −0.99 −0.32 0.11 0.11 2.89 0.88 2.73 1.90 −2.38 −2.70 −2.27 −2.27 −0.96 −0.40 0.24 −2.27 −2.74 1.86 3.37 2.12 
1441552_at Tcra 2.62 3.05 1.03 −0.11 −0.18 −0.05 0.60 3.22 3.65 1.63 −0.75 −0.86 −0.92 −0.80 −0.89 −0.64 −0.63 −0.90 −0.63 −0.53 −0.87 −0.71 
1449757_x_at Dntt (TdT) −1.68 −2.13 −8.56 0.14 −0.01 6.32 6.63 4.94 4.49 −1.94 −1.70 −1.56 −1.71 4.62 −2.05 −1.31 −1.88 −1.62 −1.75 −1.67 −1.83 −1.67 
1419711_at Cd7 −0.43 0.57 −3.54 −1.28 −1.35 −1.05 1.22 0.79 1.79 −2.32 −0.99 −2.26 −2.34 −2.03 −0.81 −1.11 3.77 2.26 0.75 0.78 −1.72 2.22 

Results are presented in log base 2. CT: CD4+CD8+; T1: CD4+CD8+; T2: CD4−CD8+; T3: CD4+CD8−; CB: CD45R+CD19+; B1-B2: CD45R+CD19+Sca-1−; B3: CD45R+lowCD19+Sca-1+. M: myeloid leukemia (CD11b+Gr1+); CE: control erythroid cells (Ter119+CD71+); E1-E3: erythroleukemias (Ter119+CD71+); Mk1-Mk3: megakaryoblastic leukemias Mk1 (cKit+CD41−); and Mk2-Mk3 (cKit+CD41+).

*

Ratio of T-CT and B-CB: mean of the deviation of T1, T2, and T3/T control value and mean of the deviation of B1, B2, and B3/B control value.

†

Amplitude of deviation from the mean calculated from the RMA values.

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