Genetic risk factors for SVT (thrombophlebitis) in patients and controls in the MEGA study
| . | Patients, thrombophlebitis . | Controls, thrombophlebitis . | ||||||
|---|---|---|---|---|---|---|---|---|
| Yes (n) . | No (n) . | Crude odds ratio (95% CI) . | Adjusted odds ratio (95% CI)* . | Yes, n . | No, n . | Crude odds ratio (95% CI) . | Adjusted odds ratio (95% CI)* . | |
| Blood group O | 96 | 1034 | Reference | Reference | 40 | 2109 | Reference | Reference |
| Blood group non-O | 286 | 2509 | 1.2 (1.0-1.6) | 1.3 (1.0-1.6) | 61 | 2457 | 1.3 (0.9-2.0) | 1.3 (0.9-2.0) |
| No factor V Leiden | 290 | 3020 | Reference | Reference | 94 | 4324 | Reference | Reference |
| Factor V Leiden | 97 | 532 | 1.9 (1.5-2.4) | 2.0 (1.6-2.6) | 7 | 244 | 1.3 (0.6-2.9) | 1.5 (0.7-3.3) |
| No prothrombin G20210A | 361 | 3373 | Reference | Reference | 99 | 4478 | Reference | Reference |
| Prothrombin G20210A | 26 | 182 | 1.3 (0.9-2.0) | 1.3 (0.9-2.0) | 2 | 91 | 1.0 (0.2-4.1) | 0.9 (0.2-3.7) |
| . | Patients, thrombophlebitis . | Controls, thrombophlebitis . | ||||||
|---|---|---|---|---|---|---|---|---|
| Yes (n) . | No (n) . | Crude odds ratio (95% CI) . | Adjusted odds ratio (95% CI)* . | Yes, n . | No, n . | Crude odds ratio (95% CI) . | Adjusted odds ratio (95% CI)* . | |
| Blood group O | 96 | 1034 | Reference | Reference | 40 | 2109 | Reference | Reference |
| Blood group non-O | 286 | 2509 | 1.2 (1.0-1.6) | 1.3 (1.0-1.6) | 61 | 2457 | 1.3 (0.9-2.0) | 1.3 (0.9-2.0) |
| No factor V Leiden | 290 | 3020 | Reference | Reference | 94 | 4324 | Reference | Reference |
| Factor V Leiden | 97 | 532 | 1.9 (1.5-2.4) | 2.0 (1.6-2.6) | 7 | 244 | 1.3 (0.6-2.9) | 1.5 (0.7-3.3) |
| No prothrombin G20210A | 361 | 3373 | Reference | Reference | 99 | 4478 | Reference | Reference |
| Prothrombin G20210A | 26 | 182 | 1.3 (0.9-2.0) | 1.3 (0.9-2.0) | 2 | 91 | 1.0 (0.2-4.1) | 0.9 (0.2-3.7) |
CI indicates confidence interval; MEGA, Multiple Environmental and Genetic Assessment of risk factors for venous thrombosis; and SVT, superficial vein thrombosis..
Adjusted for age and sex.