Causes of thrombocytosis
| Myeloid malignancy |
| Essential thrombocythemia |
| Polycythemia vera |
| Primary myelofibrosis |
| Chronic myeloid leukemia |
| Refractory anemia with ringed sideroblasts and thrombocytosis |
| Myelodysplastic syndrome associated with isolated del(5q) |
| Reactive (secondary) thrombocytosis |
| Blood loss or iron deficiency |
| Infection or inflammation |
| Disseminated malignancy |
| Drug effect (vincristine, epinephrine, all-trans-retinoic acid) |
| Hyposplenism or congenital absence of spleen |
| Hemolytic anemia |
| Familial thrombocytosis |
| Mutations in TPO, MPL, or unknown genes |
| Spurious thrombocytosis |
| Cryoglobulinemia |
| Cytoplasmic fragmentation accompanying myeloid or lymphoid neoplasia |
| Red cell fragmentation |
| Myeloid malignancy |
| Essential thrombocythemia |
| Polycythemia vera |
| Primary myelofibrosis |
| Chronic myeloid leukemia |
| Refractory anemia with ringed sideroblasts and thrombocytosis |
| Myelodysplastic syndrome associated with isolated del(5q) |
| Reactive (secondary) thrombocytosis |
| Blood loss or iron deficiency |
| Infection or inflammation |
| Disseminated malignancy |
| Drug effect (vincristine, epinephrine, all-trans-retinoic acid) |
| Hyposplenism or congenital absence of spleen |
| Hemolytic anemia |
| Familial thrombocytosis |
| Mutations in TPO, MPL, or unknown genes |
| Spurious thrombocytosis |
| Cryoglobulinemia |
| Cytoplasmic fragmentation accompanying myeloid or lymphoid neoplasia |
| Red cell fragmentation |