Results of full-dose compared with intermediate-dose melphalan
| . | Melphalan dose 200 mg/m2 (N = 231) . | Melphalan dose 100-140 mg/m2 (N = 190) . | P . |
|---|---|---|---|
| CR rate, % | 42.8 | 24.2 | < .001* |
| TRM, % | 9 | 14.2 | .12* |
| Median EFS, months | 40.9 | 21.3 | .0006* |
| Median OS, y | 8.4 | 3.8 | < .0001* |
| . | Melphalan dose 200 mg/m2 (N = 231) . | Melphalan dose 100-140 mg/m2 (N = 190) . | P . |
|---|---|---|---|
| CR rate, % | 42.8 | 24.2 | < .001* |
| TRM, % | 9 | 14.2 | .12* |
| Median EFS, months | 40.9 | 21.3 | .0006* |
| Median OS, y | 8.4 | 3.8 | < .0001* |
Statistically significant.