Multivariate analyses for RFS
| Variable* . | Hazard ratio . | 95% CI . | P . |
|---|---|---|---|
| RFS, overall cohort | |||
| WBC | 1.1 | 1.0-1.1 | .02 |
| Age, y | 1.4 | 1.2-1.6 | < .001 |
| Immunophenotype | .04 | ||
| Common vs pro-B | 3.7 | 0.9-16 | .08 |
| Pre-B vs pro-B | 2.0 | 0.4-9.0 | .38 |
| RFS, standard risk | |||
| LEF1 expression, Q4 vs Q1-Q3 | 2.4 | 1.1-5.1 | .02 |
| Variable* . | Hazard ratio . | 95% CI . | P . |
|---|---|---|---|
| RFS, overall cohort | |||
| WBC | 1.1 | 1.0-1.1 | .02 |
| Age, y | 1.4 | 1.2-1.6 | < .001 |
| Immunophenotype | .04 | ||
| Common vs pro-B | 3.7 | 0.9-16 | .08 |
| Pre-B vs pro-B | 2.0 | 0.4-9.0 | .38 |
| RFS, standard risk | |||
| LEF1 expression, Q4 vs Q1-Q3 | 2.4 | 1.1-5.1 | .02 |
Variables considered for model inclusion were: LEF1 expression (Q4 vs Q1-Q3), BCR-ABL (presence vs absence), t(4;11) (presence vs absence), WBC (10/nL increase), age (10-year increase), immunophenotype (pro-B vs common/pre-B), and CD20 (positive vs negative).