CD20 antibody complexes visualized by electron tomography.
| Sample . | GA101 . | Rituximab . |
|---|---|---|
| Tilt series | ||
| Total recorded | 25 | 15 |
| Processed | 24 | 14 |
| Immunogold markers | ||
| Total found | 98 | 194 |
| CD20 complexes | 23 | 49 |
| Multimeric states of analyzed CD20 complexes | ||
| Tetramers | 14 | 16 |
| Higher-order multimers | 4 | 1 |
| Networks | 0 | 12 |
| Unassigned | 5 | 20 |
| Subanalysis: valency of Ab binding | ||
| Monovalent Ab binding | 12 | 5 |
| Bivalent Ab binding | 1 | 5 |
| Subanalysis: tetramer conformations | ||
| Multimers | 2 | 1 |
| Tetramers | 11 | 13 |
| Open conformation | 7 | 10 |
| Closed conformation | 4 | 0 |
| Conformation not defined | 0 | 3 |
| Sample . | GA101 . | Rituximab . |
|---|---|---|
| Tilt series | ||
| Total recorded | 25 | 15 |
| Processed | 24 | 14 |
| Immunogold markers | ||
| Total found | 98 | 194 |
| CD20 complexes | 23 | 49 |
| Multimeric states of analyzed CD20 complexes | ||
| Tetramers | 14 | 16 |
| Higher-order multimers | 4 | 1 |
| Networks | 0 | 12 |
| Unassigned | 5 | 20 |
| Subanalysis: valency of Ab binding | ||
| Monovalent Ab binding | 12 | 5 |
| Bivalent Ab binding | 1 | 5 |
| Subanalysis: tetramer conformations | ||
| Multimers | 2 | 1 |
| Tetramers | 11 | 13 |
| Open conformation | 7 | 10 |
| Closed conformation | 4 | 0 |
| Conformation not defined | 0 | 3 |