Table 1

Detection of platelet-specific gene expression in thrombocytes by transcriptional profiling

Human geneLog2 ratio (T/L)P
MPL 8.72 < .001 
GP9 9.80 < .001 
ITGB3 9.25 < .001 
ITGB1 1.13 .002 
ITGA6 2.37 .004 
ITGA2 7.75 < .001 
ITGAV 4.60 < .001 
F2R 4.72 .001 
F2RL3 2.80 .007 
P2RX1 9.67 < .001 
P2RY1 3.91 < .001 
P2RY12 .58 
HTR2A 8.86 < .001 
CD36 10.01 < .001 
TBXAS1 6.22 < .001 
GP1BA 8.99 < .001 
Human geneLog2 ratio (T/L)P
MPL 8.72 < .001 
GP9 9.80 < .001 
ITGB3 9.25 < .001 
ITGB1 1.13 .002 
ITGA6 2.37 .004 
ITGA2 7.75 < .001 
ITGAV 4.60 < .001 
F2R 4.72 .001 
F2RL3 2.80 .007 
P2RX1 9.67 < .001 
P2RY1 3.91 < .001 
P2RY12 .58 
HTR2A 8.86 < .001 
CD36 10.01 < .001 
TBXAS1 6.22 < .001 
GP1BA 8.99 < .001 

Thrombocytes and lymphocytes were sorted by positive and negative selection for cell-specific markers, and gene expression analysis was performed by use of the Affymetrix chicken gene chip. The log2 of the gene expression ratio of thrombocytes vs lymphocytes (T L) and P values for genes of known platelet function are shown. All gene names used are those approved by the HUGO gene nomenclature committee (HGNC). F2R and F2RL3 refer to PAR1 and PAR3, respectively.

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