Spearman correlation of serum hepcidin concentration with clinical and laboratory variables
| . | Controls . | VHLR200W homozygotes . | ||
|---|---|---|---|---|
| N . | Rho (P) . | N . | Rho (P) . | |
| Age | 52 | 0.26 (.06) | 90 | 0.12 (.3) |
| Female sex | 52 | −0.19 (.19) | 90 | −0.02 (.8) |
| History of smoking | 52 | 0.10 (.5) | 90 | −0.05 (.7) |
| History of alcohol consumption | 52 | 0.01 (.9) | 90 | 0.16 (.12) |
| History of bleeding in the past year | 52 | −0.21 (.14) | 90 | −0.14 (.19) |
| History of thrombosis | 52 | −0.08 (.6) | 90 | 0.14 (.18) |
| Body mass index | 52 | 0.18 (.2) | 90 | 0.11 (.3) |
| Systolic blood pressure | 52 | 0.21 (.14) | 90 | −0.05 (.7) |
| Diastolic blood pressure | 52 | 0.05 (.7) | 90 | −0.07 (.5) |
| Hemoglobin | 52 | 0.29 (.038) | 90 | 0.08 (.5) |
| RBCs, ×106 | 52 | 0.20 (.16) | 90 | −0.03 (.8) |
| Mean corpuscular volume | 52 | −0.04 (.8) | 79 | 0.08 (.5) |
| Mean corpuscular hemoglobin concentration | 52 | 0.18 (.2) | 80 | −0.07 (.5) |
| WBCs | 52 | 0.30 (.031) | 90 | −0.03 (.8) |
| Platelets | 52 | 0.12 (.4) | 90 | 0.07 (.5) |
| Ferritin | 50 | 0.68 (< .0001)* | 77 | 0.36 (.001)* |
| Iron | 52 | 0.14 (.3) | 88 | 0.07 (.5) |
| Iron-binding capacity | 52 | −0.33 (.019) | 77 | −0.09 (.4) |
| Iron saturation | 52 | 0.23 (.11) | 77 | 0.12 (.3) |
| Protein | 52 | 0.32 (.021) | 88 | −0.05 (.7) |
| Albumin | 52 | 0.42 (.002)* | 88 | −0.14 (.19) |
| Globulin | 52 | 0.03 (.8) | 88 | 0.07 (.5) |
| Albumin/globulin ratio | 52 | 0.13 (.3) | 88 | −0.17 (.10) |
| Erythropoietin | 50 | −0.33 (.021) | 77 | −0.06 (.6) |
| . | Controls . | VHLR200W homozygotes . | ||
|---|---|---|---|---|
| N . | Rho (P) . | N . | Rho (P) . | |
| Age | 52 | 0.26 (.06) | 90 | 0.12 (.3) |
| Female sex | 52 | −0.19 (.19) | 90 | −0.02 (.8) |
| History of smoking | 52 | 0.10 (.5) | 90 | −0.05 (.7) |
| History of alcohol consumption | 52 | 0.01 (.9) | 90 | 0.16 (.12) |
| History of bleeding in the past year | 52 | −0.21 (.14) | 90 | −0.14 (.19) |
| History of thrombosis | 52 | −0.08 (.6) | 90 | 0.14 (.18) |
| Body mass index | 52 | 0.18 (.2) | 90 | 0.11 (.3) |
| Systolic blood pressure | 52 | 0.21 (.14) | 90 | −0.05 (.7) |
| Diastolic blood pressure | 52 | 0.05 (.7) | 90 | −0.07 (.5) |
| Hemoglobin | 52 | 0.29 (.038) | 90 | 0.08 (.5) |
| RBCs, ×106 | 52 | 0.20 (.16) | 90 | −0.03 (.8) |
| Mean corpuscular volume | 52 | −0.04 (.8) | 79 | 0.08 (.5) |
| Mean corpuscular hemoglobin concentration | 52 | 0.18 (.2) | 80 | −0.07 (.5) |
| WBCs | 52 | 0.30 (.031) | 90 | −0.03 (.8) |
| Platelets | 52 | 0.12 (.4) | 90 | 0.07 (.5) |
| Ferritin | 50 | 0.68 (< .0001)* | 77 | 0.36 (.001)* |
| Iron | 52 | 0.14 (.3) | 88 | 0.07 (.5) |
| Iron-binding capacity | 52 | −0.33 (.019) | 77 | −0.09 (.4) |
| Iron saturation | 52 | 0.23 (.11) | 77 | 0.12 (.3) |
| Protein | 52 | 0.32 (.021) | 88 | −0.05 (.7) |
| Albumin | 52 | 0.42 (.002)* | 88 | −0.14 (.19) |
| Globulin | 52 | 0.03 (.8) | 88 | 0.07 (.5) |
| Albumin/globulin ratio | 52 | 0.13 (.3) | 88 | −0.17 (.10) |
| Erythropoietin | 50 | −0.33 (.021) | 77 | −0.06 (.6) |
Significant after the Bonferroni correction for multiple comparisons.