Main patient characteristics at diagnosis according to response group
| . | CR . | nCR . | VGPR . | PR . | SD . | PD . |
|---|---|---|---|---|---|---|
| No. of patients | 84 | 66 | 54 | 114 | 12 | 14 |
| Male sex, % | 60 | 62 | 52 | 67 | 75 | 64 |
| Age, y, mean ± SD | 53 ± 8 | 55 ± 7 | 54 ± 8 | 53 ± 10 | 51 ± 7 | 53 ± 9 |
| M-protein, IgG/IgA/IgD/IgM/light chain, % | 45/27/4/1/23 | 45/27/0/2/26 | 69/21/2/0/8 | 69/18/1/0/12 | 58/16/0/0/25 | 64/21/0/0/14 |
| PS ≥ 2 (ECOG), % | 56 | 54 | 49 | 54 | 50 | 57 |
| Durie-Salmon stage, I/II/III, % | 1/27/72 | 7/14/79 | 6/33/61 | 8/20/72 | 16/33/50 | 0/43/57 |
| Serum creatinine level, μmol/L, mean ± SD | 141 ± 106 | 132 ± 79 | 141 ± 106 | 106 ± 62 | 134 ± 27 | 136 ± 79 |
| Serum albumin level, g/L, mean ± SD | 38 ± 6 | 37 ± 6 | 39 ± 7 | 38 ± 6 | 38 ± 8 | 39 ± 7 |
| Serum calcium level, μmol/L, mean ± SD | 255 ± 46 | 247 ± 35 | 237 ± 33 | 240 ± 30 | 236 ± 20 | 253 ± 23 |
| Hemoglobin level, g/dL, mean ± SD | 10.7 ± 2.5 | 10.7 ± 2.6 | 10 ± 2.4 | 11.1 ± 2 | 10.9 ± 2.1 | 9.5 ± 2.3 |
| β2 microglobulin ≥ 2.5 mg/L, % | 73 | 82 | 70 | 65 | 58 | 71 |
| LDH > normal limit, % | 18 | 13 | 9 | 4 | 10 | 20 |
| . | CR . | nCR . | VGPR . | PR . | SD . | PD . |
|---|---|---|---|---|---|---|
| No. of patients | 84 | 66 | 54 | 114 | 12 | 14 |
| Male sex, % | 60 | 62 | 52 | 67 | 75 | 64 |
| Age, y, mean ± SD | 53 ± 8 | 55 ± 7 | 54 ± 8 | 53 ± 10 | 51 ± 7 | 53 ± 9 |
| M-protein, IgG/IgA/IgD/IgM/light chain, % | 45/27/4/1/23 | 45/27/0/2/26 | 69/21/2/0/8 | 69/18/1/0/12 | 58/16/0/0/25 | 64/21/0/0/14 |
| PS ≥ 2 (ECOG), % | 56 | 54 | 49 | 54 | 50 | 57 |
| Durie-Salmon stage, I/II/III, % | 1/27/72 | 7/14/79 | 6/33/61 | 8/20/72 | 16/33/50 | 0/43/57 |
| Serum creatinine level, μmol/L, mean ± SD | 141 ± 106 | 132 ± 79 | 141 ± 106 | 106 ± 62 | 134 ± 27 | 136 ± 79 |
| Serum albumin level, g/L, mean ± SD | 38 ± 6 | 37 ± 6 | 39 ± 7 | 38 ± 6 | 38 ± 8 | 39 ± 7 |
| Serum calcium level, μmol/L, mean ± SD | 255 ± 46 | 247 ± 35 | 237 ± 33 | 240 ± 30 | 236 ± 20 | 253 ± 23 |
| Hemoglobin level, g/dL, mean ± SD | 10.7 ± 2.5 | 10.7 ± 2.6 | 10 ± 2.4 | 11.1 ± 2 | 10.9 ± 2.1 | 9.5 ± 2.3 |
| β2 microglobulin ≥ 2.5 mg/L, % | 73 | 82 | 70 | 65 | 58 | 71 |
| LDH > normal limit, % | 18 | 13 | 9 | 4 | 10 | 20 |
PS indicates performance status; ECOG, Eastern Cooperative Oncology Group; and LDH, lactate dehydrogenase.