Observed and expected cancers and SIRs among Danish patients diagnosed with PV during 1977-2008 and followed for new primary cancers
| . | Person-years of patients with PV, n . | PV patients with nonhematologic cancers, n . | Nonhematologic cancers expected, n . | SIR (95% CI) . | PV patients with hematologic cancers, n . | Hematologic cancers expected, n . | SIR (95% CI) . |
|---|---|---|---|---|---|---|---|
| All | 31 270 | 704 | 493.5 | 1.4 (1.3-1.5) | 115 | 30.3 | 3.8 (3.1-4.6) |
| Women | 12 493 | 278 | 189.7 | 1.5 (1.3-1.7) | 47 | 10.6 | 4.4 (3.2-5.9) |
| Men | 18 776 | 426 | 303.8 | 1.4 (1.3-1.5) | 68 | 19.7 | 3.5 (2.7-4.4) |
| Age at PV diagnosis, y | |||||||
| 20-49 | 8460 | 97 | 50.9 | 1.9 (1.6-2.3) | 15 | 3.1 | 4.9 (2.7-8.1) |
| 50-69 | 15 685 | 387 | 263.5 | 1.5 (1.3-1.6) | 63 | 15.8 | 4.0 (3.1-5.1) |
| 70+ | 7124 | 220 | 179.0 | 1.2 (1.1-1.4) | 37 | 11.5 | 2.3 (2.3-4.4) |
| Year of PV diagnosis | |||||||
| 1977-1994 | 22 693 | 506 | 343.3 | 1.5 (1.4-1.6) | 82 | 21.1 | 3.9 (3.1-4.8) |
| 1995-2008 | 8577 | 198 | 150.1 | 1.3 (1.1-1.5) | 33 | 9.3 | 3.6 (2.5-5.0) |
| Follow-up time | |||||||
| Year 2 | 4339 | 79 | 65.6 | 1.2 (1.0-1.5) | 11 | 4.0 | 2.8 (1.4-5.0) |
| Years 3-5 | 10 005 | 212 | 153.9 | 1.4 (1.2-1.6) | 35 | 9.4 | 3.7 (2.6-5.2) |
| Years 6+ | 16 926 | 413 | 273.9 | 1.5 (1.4-1.7) | 69 | 17 | 4.1 (3.2-5.1) |
| Hospital contact type (from 1995 on) | |||||||
| Outpatient only | 4395 | 89 | 74.1 | 1.2 (1.0-1.5) | 14 | 4.5 | 3.1 (1.7-5.2) |
| Inpatient admission | 4182 | 109 | 76.1 | 1.4 (1.2-1.7) | 19 | 4.7 | 4.0 (2.4-6.3) |
| . | Person-years of patients with PV, n . | PV patients with nonhematologic cancers, n . | Nonhematologic cancers expected, n . | SIR (95% CI) . | PV patients with hematologic cancers, n . | Hematologic cancers expected, n . | SIR (95% CI) . |
|---|---|---|---|---|---|---|---|
| All | 31 270 | 704 | 493.5 | 1.4 (1.3-1.5) | 115 | 30.3 | 3.8 (3.1-4.6) |
| Women | 12 493 | 278 | 189.7 | 1.5 (1.3-1.7) | 47 | 10.6 | 4.4 (3.2-5.9) |
| Men | 18 776 | 426 | 303.8 | 1.4 (1.3-1.5) | 68 | 19.7 | 3.5 (2.7-4.4) |
| Age at PV diagnosis, y | |||||||
| 20-49 | 8460 | 97 | 50.9 | 1.9 (1.6-2.3) | 15 | 3.1 | 4.9 (2.7-8.1) |
| 50-69 | 15 685 | 387 | 263.5 | 1.5 (1.3-1.6) | 63 | 15.8 | 4.0 (3.1-5.1) |
| 70+ | 7124 | 220 | 179.0 | 1.2 (1.1-1.4) | 37 | 11.5 | 2.3 (2.3-4.4) |
| Year of PV diagnosis | |||||||
| 1977-1994 | 22 693 | 506 | 343.3 | 1.5 (1.4-1.6) | 82 | 21.1 | 3.9 (3.1-4.8) |
| 1995-2008 | 8577 | 198 | 150.1 | 1.3 (1.1-1.5) | 33 | 9.3 | 3.6 (2.5-5.0) |
| Follow-up time | |||||||
| Year 2 | 4339 | 79 | 65.6 | 1.2 (1.0-1.5) | 11 | 4.0 | 2.8 (1.4-5.0) |
| Years 3-5 | 10 005 | 212 | 153.9 | 1.4 (1.2-1.6) | 35 | 9.4 | 3.7 (2.6-5.2) |
| Years 6+ | 16 926 | 413 | 273.9 | 1.5 (1.4-1.7) | 69 | 17 | 4.1 (3.2-5.1) |
| Hospital contact type (from 1995 on) | |||||||
| Outpatient only | 4395 | 89 | 74.1 | 1.2 (1.0-1.5) | 14 | 4.5 | 3.1 (1.7-5.2) |
| Inpatient admission | 4182 | 109 | 76.1 | 1.4 (1.2-1.7) | 19 | 4.7 | 4.0 (2.4-6.3) |