Table 2 Type and specificity of... | American Society of Hematology

Table 2

Type and specificity of donor-specific anti-HLA Abs in matched unrelated donor transplant recipients

n	Anti-DP DSA	MFI value before first SCT	Subunit	Epitope*	Ags within epitope, n†	MFI for epitope‡	Engrafted	Second SCT	MFI second SCT	Engrafted
1	0401	1558	DPB1	A 56	4	880-1558	Y	N	N/A	N/A
2	0301	4341	DPB1	EAV 85-87	9	2723-8531	N	N	N/A	N/A
3	0301	2759	DPB1	EAV 85-87	11	971-3072	N	Y	0	Y
4	0101	3733	DPB1	EAV 85-87	11	1787-7781	Y	N	N/A	N/A
5	0101	4924	DPB1	EAV 85-87	11	552-4924	Y	N	N/A	N/A
5	1101	1019
6	1401	5597	DPB1	E 56	8	4835-8419	Y	N	N/A	N/A
7	2001	3990	DPB1	K/R 69-M 76	6	1583-6411	N	N	N/A	N/A
8	1001	9485	DPB1	EAV 85-87	10	2320-9485	Y	N	N/A	N/A

n	Anti-DP DSA	MFI value before first SCT	Subunit	Epitope*	Ags within epitope, n†	MFI for epitope‡	Engrafted	Second SCT	MFI second SCT	Engrafted
1	0401	1558	DPB1	A 56	4	880-1558	Y	N	N/A	N/A
2	0301	4341	DPB1	EAV 85-87	9	2723-8531	N	N	N/A	N/A
3	0301	2759	DPB1	EAV 85-87	11	971-3072	N	Y	0	Y
4	0101	3733	DPB1	EAV 85-87	11	1787-7781	Y	N	N/A	N/A
5	0101	4924	DPB1	EAV 85-87	11	552-4924	Y	N	N/A	N/A
5	1101	1019
6	1401	5597	DPB1	E 56	8	4835-8419	Y	N	N/A	N/A
7	2001	3990	DPB1	K/R 69-M 76	6	1583-6411	N	N	N/A	N/A
8	1001	9485	DPB1	EAV 85-87	10	2320-9485	Y	N	N/A	N/A

SCT indicates stem cell transplantation; and N/A, not applicable.

Amino acid residues recognized by the DSAs in the donor.

Number of single Ag preparations sharing the DSA epitope.

Range of MFIs detected on single Ag preparations bearing the epitope detected by the DSA.