Table 3 Impact of HLA matching and... | American Society of Hematology

Table 3

Impact of HLA matching and anti-HLA Abs on the probability of engraftment using Bayesian logistic regression models

Variable	Mean	SD	Posterior 95% CI		Probability of a beneficial effect
Variable	Mean	SD	2.50%	97.50%	Probability of a beneficial effect
Full model
Intercept	3.296	0.658	2.140	4.674
HEL match (vs HEL mismatch)	0.432	0.687	-1.021	1.682	.761
LEL match (vs LEL mismatch)	0.413	0.675	-0.772	1.888	.729
AHA⁺, DSA⁺ (vs AHA−, DSA⁻)	−3.114	0.835	−4.703	−1.470	< .001
AHA⁺, DSA⁻ (vs AHA⁻, DSA⁻)	−0.315	0.598	−1.456	0.919	.285
Combining AHA⁺DSA⁻ with AHA⁻
Intercept	3.246	0.689	2.065	4.758
HEL match (vs HEL mismatch)	0.376	0.731	−1.156	1.663	.719
LEL match (vs LEL mismatch)	0.467	0.698	−0.768	1.922	.758
AHA⁺, DSA⁺ (vs DSA⁻)	−3.070	0.809	−4.647	−1.302	< .001
Combining HEL and LEL mismatch
Intercept	3.506	0.264	3.027	4.050
HEL and LEL match (vs any mismatch in HEL or LEL)	0.876	0.860	−0.539	2.769	.857
AHA⁺, DSA⁺ (vs DSA⁻)	−2.923	0.849	−4.507	−1.144	.001

Variable	Mean	SD	Posterior 95% CI		Probability of a beneficial effect
Variable	Mean	SD	2.50%	97.50%	Probability of a beneficial effect
Full model
Intercept	3.296	0.658	2.140	4.674
HEL match (vs HEL mismatch)	0.432	0.687	-1.021	1.682	.761
LEL match (vs LEL mismatch)	0.413	0.675	-0.772	1.888	.729
AHA⁺, DSA⁺ (vs AHA−, DSA⁻)	−3.114	0.835	−4.703	−1.470	< .001
AHA⁺, DSA⁻ (vs AHA⁻, DSA⁻)	−0.315	0.598	−1.456	0.919	.285
Combining AHA⁺DSA⁻ with AHA⁻
Intercept	3.246	0.689	2.065	4.758
HEL match (vs HEL mismatch)	0.376	0.731	−1.156	1.663	.719
LEL match (vs LEL mismatch)	0.467	0.698	−0.768	1.922	.758
AHA⁺, DSA⁺ (vs DSA⁻)	−3.070	0.809	−4.647	−1.302	< .001
Combining HEL and LEL mismatch
Intercept	3.506	0.264	3.027	4.050
HEL and LEL match (vs any mismatch in HEL or LEL)	0.876	0.860	−0.539	2.769	.857
AHA⁺, DSA⁺ (vs DSA⁻)	−2.923	0.849	−4.507	−1.144	.001

AHA indicates anti-HLA Abs.