Table 1

Comparative radiation absorbed doses after anti-CD45 PRIT using 90Y- or 213Bi-DOTA-biotin

Tissue90Y-DOTA-biotin, Gy213Bi-DOTA-biotin, Gy
Blood 2.9 9.8 
Spleen 2.3 2.3 
Kidney 5.7 5.4 
Tumor 13.1 17.0 
Tissue90Y-DOTA-biotin, Gy213Bi-DOTA-biotin, Gy
Blood 2.9 9.8 
Spleen 2.3 2.3 
Kidney 5.7 5.4 
Tumor 13.1 17.0 

Absorbed doses to blood, spleen, kidney, and tumor 10 minutes after delivery of 213Bi-DOTA-biotin and 1 hour after 90Y-DOTA-biotin was calculated for each radionuclide to deliver 5 Gy in the liver.

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