Patient and clinical characteristics (N = 53)
| Men, n (%) | 30 (57) |
| Median age, y (range) | 60.5 (34.7-80.9) |
| Race, n (%) | |
| White | 52 (98) |
| Black | 1 (2) |
| Symptoms and signs, n (%) | |
| Fatigue | 32 (60) |
| Lower extremity edema | 23 (43) |
| Paresthesias | 17 (32) |
| Weight loss | 17 (32) |
| Dyspnea on exertion | 15 (28) |
| Carpal tunnel syndrome | 14 (26) |
| Enlarged tongue | 11 (21) |
| Hepatomegaly | 9 (17) |
| Neuropathy | 8 (15) |
| Purpura | 7 (13) |
| Bleeding | 3 (6) |
| Pain | 2 (4) |
| Status at last follow-up, n (%) | |
| Dead | 41 (77) |
| Alive | 11 (21) |
| Lost to follow-up | 1 (2) |
| Cause of death, n (%)* | |
| Unknown | 24 (59) |
| Cardiac failure or arrest | 10 (24) |
| Infection | 3 (7) |
| Myeloma | 1 (2) |
| Renal failure | 1 (2) |
| Cachexia | 1 (2) |
| Treatment-related leukemia | 1 (2) |
| Men, n (%) | 30 (57) |
| Median age, y (range) | 60.5 (34.7-80.9) |
| Race, n (%) | |
| White | 52 (98) |
| Black | 1 (2) |
| Symptoms and signs, n (%) | |
| Fatigue | 32 (60) |
| Lower extremity edema | 23 (43) |
| Paresthesias | 17 (32) |
| Weight loss | 17 (32) |
| Dyspnea on exertion | 15 (28) |
| Carpal tunnel syndrome | 14 (26) |
| Enlarged tongue | 11 (21) |
| Hepatomegaly | 9 (17) |
| Neuropathy | 8 (15) |
| Purpura | 7 (13) |
| Bleeding | 3 (6) |
| Pain | 2 (4) |
| Status at last follow-up, n (%) | |
| Dead | 41 (77) |
| Alive | 11 (21) |
| Lost to follow-up | 1 (2) |
| Cause of death, n (%)* | |
| Unknown | 24 (59) |
| Cardiac failure or arrest | 10 (24) |
| Infection | 3 (7) |
| Myeloma | 1 (2) |
| Renal failure | 1 (2) |
| Cachexia | 1 (2) |
| Treatment-related leukemia | 1 (2) |
n = 41.