Characteristics of patients with BCR− B cells
| . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . |
|---|---|---|---|---|
| Male/female | F | F | M | M |
| Age at diagnosis | 9 mo | 10 mo | 24 mo | 4 y |
| Age at most recent evaluation | 22 y | 8 y | 15 y | 11 y |
| Age at most recent contact | 34 y | 8 y | 15 y | 20 y |
| Presenting findings | Pneumococcal meningitis | Recurrent otitis | Vaccine-associated polio | Recurrent otitis and arthritis |
| Associated findings | Eosinophilic dermatitis | Hepatomegaly | ||
| Serum IgG | 859 mg/dL* | < 33 mg/dL | 844 mg/dL* | < 100 mg/dL |
| Serum IgM | < 7 mg/dL | 14 mg/dL | < 1 mg/dL | < 5 mg/dL |
| Serum IgA | < 7 mg/dL | < 7mg/dL | 10 mg/dL | < 5 mg/dL |
| Percent CD19+ | 0.44 | 2.5 | 0.22 | 1.5 |
| Percent CD3+ | 91 | 98 | 92.1 | |
| Percent CD56/16+ | 7 | 2 | 5 |
| . | Patient 1 . | Patient 2 . | Patient 3 . | Patient 4 . |
|---|---|---|---|---|
| Male/female | F | F | M | M |
| Age at diagnosis | 9 mo | 10 mo | 24 mo | 4 y |
| Age at most recent evaluation | 22 y | 8 y | 15 y | 11 y |
| Age at most recent contact | 34 y | 8 y | 15 y | 20 y |
| Presenting findings | Pneumococcal meningitis | Recurrent otitis | Vaccine-associated polio | Recurrent otitis and arthritis |
| Associated findings | Eosinophilic dermatitis | Hepatomegaly | ||
| Serum IgG | 859 mg/dL* | < 33 mg/dL | 844 mg/dL* | < 100 mg/dL |
| Serum IgM | < 7 mg/dL | 14 mg/dL | < 1 mg/dL | < 5 mg/dL |
| Serum IgA | < 7 mg/dL | < 7mg/dL | 10 mg/dL | < 5 mg/dL |
| Percent CD19+ | 0.44 | 2.5 | 0.22 | 1.5 |
| Percent CD3+ | 91 | 98 | 92.1 | |
| Percent CD56/16+ | 7 | 2 | 5 |
On gammaglobulin therapy.