Table 6

Multivariate analysis of factors affecting overall survival

Relative risk of death (95% CI)P overall
Main effect  < .001 
    1989-1994 1.00 (reference)  
    1995-2000 0.83 (0.69-1.01) .05 
    2001-2005*   
        ≤ 6 mo after transplantation 0.41 (0.32-0.53) < .001 
        > 6 mo after transplantation 0.98 (0.76-1.26) .86 
Other significant factors   
    Age, continuous 1.01 (1.00-1.02) .04 
    Time from diagnosis to transplant   
        ≤ 24 mo 1.00 (reference)  
        > 24 mo 1.24 (1.06-1.45) .01 
    Donor   
        HLA-identical sibling 1.00 (reference)  
        Others 1.79 (1.52-2.11) < .001 
Relative risk of death (95% CI)P overall
Main effect  < .001 
    1989-1994 1.00 (reference)  
    1995-2000 0.83 (0.69-1.01) .05 
    2001-2005*   
        ≤ 6 mo after transplantation 0.41 (0.32-0.53) < .001 
        > 6 mo after transplantation 0.98 (0.76-1.26) .86 
Other significant factors   
    Age, continuous 1.01 (1.00-1.02) .04 
    Time from diagnosis to transplant   
        ≤ 24 mo 1.00 (reference)  
        > 24 mo 1.24 (1.06-1.45) .01 
    Donor   
        HLA-identical sibling 1.00 (reference)  
        Others 1.79 (1.52-2.11) < .001 
*

Different relative risks in early and late time periods after transplantation indicates a covariate with nonproportional hazards (P < .001).

Three degrees of freedom.

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