Expression of genes comprising the macrophage signature
| Symbol . | Official full name . | c-Maf+/+ signal . | c-Maf−/− signal . | Fold . |
|---|---|---|---|---|
| VCAM-1 | Vascular cell adhesion molecule 1 | 8.3 | 1.6 | 0.19 |
| Mrc1 | Mannose receptor, C type 1 | 19.8 | 5.7 | 0.29 |
| Csf1r | Colony stimulating factor 1 receptor | 45 | 16.8 | 0.37 |
| Sell | Selectin, lymphocyte | 26.7 | 10 | 0.37 |
| Lamp2 | Lysosomal-associated membrane protein 2 | 8.9 | 3.3 | 0.37 |
| Itgav | Integrin α V | 1.2 | 0.5 | 0.41 |
| Maea (EMP) | Macrophage erythroblast attacher | 26.2 | 14.5 | 0.55 |
| Emr1 (F4/80) | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 71.4 | 48.1 | 0.67 |
| Itgam (Mac-1) | Integrin α M | 5.8 | 3.9 | 0.67 |
| Cd163 | CD163 antigen | 0.6 | 0.4 | 0.67 |
| Cd14 | CD14 antigen | 11.8 | 9.4 | 0.80 |
| Fcgr1 | Fc receptor, IgG, high-affinity I | 15.7 | 17.6 | 1.12 |
| Symbol . | Official full name . | c-Maf+/+ signal . | c-Maf−/− signal . | Fold . |
|---|---|---|---|---|
| VCAM-1 | Vascular cell adhesion molecule 1 | 8.3 | 1.6 | 0.19 |
| Mrc1 | Mannose receptor, C type 1 | 19.8 | 5.7 | 0.29 |
| Csf1r | Colony stimulating factor 1 receptor | 45 | 16.8 | 0.37 |
| Sell | Selectin, lymphocyte | 26.7 | 10 | 0.37 |
| Lamp2 | Lysosomal-associated membrane protein 2 | 8.9 | 3.3 | 0.37 |
| Itgav | Integrin α V | 1.2 | 0.5 | 0.41 |
| Maea (EMP) | Macrophage erythroblast attacher | 26.2 | 14.5 | 0.55 |
| Emr1 (F4/80) | EGF-like module containing, mucin-like, hormone receptor-like sequence 1 | 71.4 | 48.1 | 0.67 |
| Itgam (Mac-1) | Integrin α M | 5.8 | 3.9 | 0.67 |
| Cd163 | CD163 antigen | 0.6 | 0.4 | 0.67 |
| Cd14 | CD14 antigen | 11.8 | 9.4 | 0.80 |
| Fcgr1 | Fc receptor, IgG, high-affinity I | 15.7 | 17.6 | 1.12 |
Fetal liver macrophages were purified by flow cytometry from c-Maf+/+ or c-Maf−/− fetal livers. The fold change in the gene expression was determined by dividing the signal obtained with c-Maf−/− fetal liver macrophage RNA by the signal obtained with c-Maf+/+ RNA.